Rv3567c

Tuberculist information
Gene namehsaB
Protein functionPossible oxidoreductase. Possible 3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione hydroxylase.
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)4008.72
Molecular mass(da)20539.3
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 187
	  		  	1    MSAQIDPRTFRSVLGQFCTGITVITTVHDDVPVGFACQSFAALSLEPPLVLFCPTKVSRS   60
			  	61   WQAIEASGRFCVNVLTEKQKDVSARFGSKEPDKFAGIDWRPSELGSPIIEGSLAYIDCTV  120
			  	121  ASVHDGGDHFVVFGAVESLSEVPAVKPRPLLFYRGDYTGIEPEKTTPAHWRDDLEAFLIT  180
			  	181  TTQDTWL

Known structures in the PDB
No Known structures
1 19 37 55 73 91 109 127 145 163 181 Range: 14 to 161  |  Coverage: 78% Flavin_Reduct Range: 5 to 162  |  Coverage: 83% 1 Range: 1 to 185  |  Coverage: 98% 1
Number of amino acids : 187
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Flavin_ReductPF0161314-161
Mtb Structural Proteome models
Model Number1
Model nameRv3567c
Template1RZ1    APDBCREDO
Template coverage1_153
Template Identity(%)32.7
Model coverage(%)84.0
Normalized DOPE score-0.706

Structure Models from Chopin
Model Number1
Profileb.45.1.2 - 2.30.110.10
Click for model details
zscore19.95
Residue begin1
Residue end185
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3567cGene nameConfidence Score
Rv3570chsaA0.986
Rv3570chsaA0.986
Rv3569chsaD0.984
Rv3568chsaC0.972
Rv3566ARv3566A0.922
Rv3566cnat0.905
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
flavin mononucleotidePubChem0.717456.344