Rv3553

Tuberculist information
Gene nameRv3553
Protein functionPossible oxidoreductase
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)3991.62
Molecular mass(da)36830.8
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 355
	  		  	1    MRLRTPLTELIGIEHPVVQTGMGWVAGARLVSATANAGGLGILASATMTLDELAAAITKV   60
			  	61   KAVTDKPFGVNIRADAADAGDRVELMIREGVRVASFALAPKQQLIARLKEAGAVVIPSIG  120
			  	121  AAKHARKVAAWGADAMIVQGGEGGGHTGPVATTLLLPSVLDAVAGTGIPVIAAGGFFDGR  180
			  	181  GLAAALCYGAAGVAMGTRFLLTSDSTVPDAVKRRYLQAGLDGTVVTTRVDGMPHRVLRTE  240
			  	241  LVEKLESGSRARGFAAALRNAGKFRRMSQMTWRSMIRDGLTMRHGKELTWSQVLMAANTP  300
			  	301  MLLKAGLVDGNTEAGVLASGQVAGILDDLPSCKELIESIVLDAITHLQTASALVE

Known structures in the PDB
No Known structures
1 36 71 106 141 176 211 246 281 316 351 Range: 4 to 342  |  Coverage: 95% NMO Range: 3 to 354  |  Coverage: 98% 1 Range: 1 to 279  |  Coverage: 78% 1
Number of amino acids : 355
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
NMOPF030604-342
Mtb Structural Proteome models
Model Number1
Model nameRv3553
Template2GJL    APDBCREDO
Template coverage4_325
Template Identity(%)34.5
Model coverage(%)98.9
Normalized DOPE score0.173

Structure Models from Chopin
Model Number1
Profilec.1.5.1 - 3.20.20.70
Click for model details
zscore10
Residue begin1
Residue end279
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3553Gene nameConfidence Score
Rv3552Rv35520.939
Rv3551Rv35510.92
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
flavin mononucleotidePubChem0.706456.344