Rv3552

Tuberculist information
Gene nameRv3552
Protein functionPossible CoA-transferase (beta subunit)
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)3990.77
Molecular mass(da)27360.9
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 250
	  		  	1    VSTRAEVCAVACAELFRDAGEIMISPMTNMASVGARLARLTFAPDILLTDGEAQLLADTP   60
			  	61   ALGKTGAPNRIEGWMPFGRVFETLAWGRRHVVMGANQVDRYGNQNISAFGPLQRPTRQMF  120
			  	121  GVRGSPGNTINHATSYWVGNHCKRVFVEAVDVVSGIGYDKVDPDNPAFRFVNVYRVVSNL  180
			  	181  GVFDFGGPDHSMRAVSLHPGVTPGDVRDATSFEVHDLDAAEQTRLPTDDELHLIRAVIDP  240
			  	241  KSLRDREIRS

Known structures in the PDB
No Known structures
1 26 51 76 101 126 151 176 201 226 251 Range: 3 to 246  |  Coverage: 97% NagB/RpiA/CoA transferase-like Range: 3 to 240  |  Coverage: 94% 1 Range: 1 to 249  |  Coverage: 99% 1
Number of amino acids : 250
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
NagB/RpiA/CoA transferase-likec.124.13-246
Mtb Structural Proteome models
Model Number1
Model nameRv3552
Template1POI    BPDBCREDO
Template coverage8_254
Template Identity(%)27.7
Model coverage(%)94.4
Normalized DOPE score0.039

Structure Models from Chopin
Model Number1
Profilec.124.1.3 - 3.40.810.20
Click for model details
zscore19.64
Residue begin1
Residue end249
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3552Gene nameConfidence Score
Rv3551Rv35510.999
Rv3550echA200.996
Rv3560cfadE300.984
Rv3560cfadE300.984
Rv3560cfadE300.984
Rv3562fadE310.983
Rv3562fadE310.983
Rv3562fadE310.983
Rv3563fadE320.975
Rv3563fadE320.975
Rv3564fadE330.942
Rv3564fadE330.942
Rv3553Rv35530.939
Rv1933cfadE180.924
Rv1933cfadE180.924
Rv1934cfadE170.921
Rv1934cfadE170.921
Rv1934cfadE170.921
Rv3504fadE260.917
Rv3504fadE260.917
Rv3504fadE260.917
Rv3548cRv3548c0.916
Rv2724cfadE200.911
Rv0752cfadE90.911
Rv2724cfadE200.911
Rv2724cfadE200.911
Rv0215cfadE30.911
Rv0215cfadE30.911
Rv0752cfadE90.911
Rv0215cfadE30.911
Rv0752cfadE90.911
Rv2789cfadE210.91
Rv2789cfadE210.91
Rv2789cfadE210.91
Rv3543cfadE290.905
Rv3274cfadE250.905
Rv3543cfadE290.905
Rv3274cfadE250.905
Rv3543cfadE290.905
Rv3274cfadE250.905
Rv3549cRv3549c0.904
Rv0244cfadE50.903
Rv0244cfadE50.903
Rv3568chsaC0.903
Rv0244cfadE50.903
Rv0244cfadE50.903
Rv0244cfadE50.903
Rv3139fadE240.902
Rv3139fadE240.902
Rv3139fadE240.902
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
succinyl-CoAPubChem0.913867.607
naphthyl-2-methyl-succinyl-CoAPubChem0.91007.79
geranic acidPubChem0.9168.233
2-naphthoyl-CoAPubChem0.9921.699
2-naphthoic acidPubChem0.9172.18