Tuberculist information
Gene nameltp4
Protein functionPossible lipid transfer protein or keto acyl-CoA thiolase Ltp4
Functional category(tuberculist)lipid metabolism
Gene location(kb)3958.45
Molecular mass(da)37864.9
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 354
	  		  	1    MSVRDIAVVGFAHAPHVRRTDGTTNGVEMLMPCFAQLYDELGITKADIGFWCSGSSDYLA   60
			  	61   GRAFSFISAIDSIGAVPPINESHVEMDAAWALYEAYIKLLTGEVDTALVYGFGKSSAGTL  120
			  	121  RRVLSRQTDPYTVAPLWPDSVSMAGLQARLGLDSGKWTHEQMARVAFDSFTNARRVDSVE  180
			  	181  PPITVGELLARPFFADPLRRHDIAPITDGAAAVVLAADNRARELRENPAWITGIEHRIES  240
			  	241  PALGARDITESPSTKLAAKIATGGHTGDIDVAEIHGPFTHQHLIVAEAIRIPGKTKVNPS  300
			  	301  GGPLAANPMFAAGLERIGFAAQHTWDGSARRVLAHATSGPALQQNLVAVMEGRG
			  			

Known structures in the PDB
No Known structures
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Thiolase_NPF001084-217
Mtb Structural Proteome models
Model Number1
Model nameRv3522
Template1WDK    CPDBCREDO
Template coverage3_389
Template Identity(%)19.1
Model coverage(%)98.9
Normalized DOPE score0.235

Structure Models from Chopin
Model Number1
Profilec.95.1.1
Click for model details
zscore5.52
Residue begin1
Residue end342
Binding pockets
STRING
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Protein interacting with Rv3522Gene nameConfidence Score
Rv3521Rv35210.953
Rv3523ltp30.926
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions