Rv3376

Tuberculist information
Gene nameRv3376
Protein functionConserved hypothetical protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)3790.16
Molecular mass(da)23645.8
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 217
	  		  	1    LSISAVVFDRDGVLTSFDWTRAEEDVRRITGLPLEEIERRWGGWLNGLTIDDAFVETQPI   60
			  	61   SEFLSSLARELELGSKARDELVRLDYMAFAQGYPDARPALEEARRRGLKVGVLTNNSLLV  120
			  	121  SARSLLQCAALHDLVDVVLSSQMIGAAKPDPRAYQAIAEALGVSTTSCLFFDDIADWVEG  180
			  	181  ARCAGMRAYLVDRSGQTRDGVVRDLSSLGAILDGAGP

Known structures in the PDB
No Known structures
1 22 43 64 85 106 127 148 169 190 211 Range: 6 to 191  |  Coverage: 85% HAD_2 Range: 2 to 216  |  Coverage: 98% 1 Range: 1 to 217  |  Coverage: 99% 1
Number of amino acids : 217
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
HAD_2PF134196-191
Mtb Structural Proteome models
Model Number1
Model nameRv3376
Template1QQ5    APDBCREDO
Template coverage1_245
Template Identity(%)27.4
Model coverage(%)98.6
Normalized DOPE score-0.627

Structure Models from Chopin
Model Number1
Profilec.108.1.6
Click for model details
zscore25.42
Residue begin1
Residue end217
Binding pockets
STRING
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Protein interacting with Rv3376Gene nameConfidence Score
Rv3375amiD0.929
Rv3373echA180.927
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions