Rv3287c

Tuberculist information
Gene namersbW
Protein functionAnti-sigma factor RsbW (sigma negative effector)
Functional category(tuberculist)information pathways
Gene location(kb)3668.95
Molecular mass(da)15550.6
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 145
	  		  	1    MADSDLPTKGRQRGVRAVELNVAARLENLALLRTLVGAIGTFEDLDFDAVADLRLAVDEV   60
			  	61   CTRLIRSALPDATLRLVVDPRKDEVVVEASAACDTHDVVAPGSFSWHVLTALADDVQTFH  120
			  	121  DGRQPDVAGSVFGITLTARRAASSR

Known structures in the PDB
No Known structures
1 15 29 43 57 71 85 99 113 127 141 Range: 23 to 118  |  Coverage: 65% HATPase_c_2 Range: 16 to 134  |  Coverage: 81% 1 Range: 1 to 145  |  Coverage: 99% 1
Number of amino acids : 145
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
HATPase_c_2PF1358123-118
Mtb Structural Proteome models
Model Number1
Model nameRv3287c
Template1TH8    APDBCREDO
Template coverage3_134
Template Identity(%)16.0
Model coverage(%)81.4
Normalized DOPE score-0.618

Structure Models from Chopin
Model Number1
Profiled.122.1.3 - 3.30.565.10
Click for model details
zscore5.46
Residue begin1
Residue end145
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3287cGene nameConfidence Score
Rv3286csigF0.994
Rv3286csigF0.994
Rv3286csigF0.994
Rv3288cusfY0.977
Rv1904Rv19040.945
Rv1365crsfA0.94
Rv2638Rv26380.917
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions