Rv1365c

Tuberculist information
Gene namersfA
Protein functionAnti-anti-sigma factor RsfA (anti-sigma factor antagonist) (regulator of sigma F A)
Functional category(tuberculist)information pathways
Gene location(kb)1537.78
Molecular mass(da)13589.4
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 128
	  		  	1    MNPTQAGSFTTPVSNALKATIQHHDSAVIIHARGEIDAANEHTWQDLVTKAAAATTAPEP   60
			  	61   LVVNLNGLDFMGCCAVAVLAHEAERCRRRGVDVRLVSRDRAVARIIHACGYGDVLPVHPT  120
			  	121  TESALSAT

Known structures in the PDB
No Known structures
1 13 25 37 49 61 73 85 97 109 121 Range: 18 to 124  |  Coverage: 82% STAS Range: 16 to 127  |  Coverage: 86% 1 Range: 13 to 128  |  Coverage: 89% 1
Number of amino acids : 128
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
STASPF0174018-124
Mtb Structural Proteome models
Model Number1
Model nameRv1365c
Template1TH8    BPDBCREDO
Template coverage2_112
Template Identity(%)21.6
Model coverage(%)86.7
Normalized DOPE score-0.82

Structure Models from Chopin
Model Number1
Profilec.13.2.1 - 3.30.750.24
Click for model details
zscore18.7
Residue begin13
Residue end128
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1365cGene nameConfidence Score
Rv1364cRv1364c0.944
Rv1364cRv1364c0.944
Rv1364cRv1364c0.944
Rv1364cRv1364c0.944
Rv3287crsbW0.94
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions