Rv2922A

Tuberculist information
Gene nameacyP
Protein functionProbable acylphosphatase AcyP (acylphosphate phosphohydrolase)
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)3237.82
Molecular mass(da)10205.6
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 93
	  		  	1    MSAPDVRLTAWVHGWVQGVGFRWWTRCRALELGLTGYAANHADGRVLVVAQGPRAACQKL   60
			  	61   LQLLQGDTTPGRVAKVVADWSQSTEQITGFSER

Known structures in the PDB
No Known structures
1 10 19 28 37 46 55 64 73 82 91 Range: 1 to 93  |  Coverage: 98% Acylphosphatase Range: 7 to 82  |  Coverage: 80% 1
Number of amino acids : 93
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
AcylphosphatasePF007081-93
Mtb Structural Proteome models
Model Number1
Model nameRv2922A
Template1ULR    APDBCREDO
Template coverage3_78
Template Identity(%)48.7
Model coverage(%)79.8
Normalized DOPE score-1.193

Structure Models from Chopin
CHOPIN models not available for this query
Binding pockets
STRING
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Protein interacting with Rv2922AGene nameConfidence Score
Rv2923cRv2923c0.965
Rv3667acs0.925
Rv3667acs0.925
Rv0408pta0.902
Rv0408pta0.902
Rv0408pta0.902
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
acetyl phosphatePubChem0.9140.032
acetatePubChem0.959.044
benzoic acidPubChem0.9121.113
phosphatePubChem0.73196.9872