Rv2875

Tuberculist information
Gene namempt70
Protein functionMajor secreted immunogenic protein Mpt70
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)3187.03
Molecular mass(da)19072.5
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 193
	  		  	1    MKVKNTIAATSFAAAGLAALAVAVSPPAAAGDLVGPGCAEYAAANPTGPASVQGMSQDPV   60
			  	61   AVAASNNPELTTLTAALSGQLNPQVNLVDTLNSGQYTVFAPTNAAFSKLPASTIDELKTN  120
			  	121  SSLLTSILTYHVVAGQTSPANVVGTRQTLQGASVTVTGQGNSLKVGNADVVCGGVSTANA  180
			  	181  TVYMIDSVLMPPA

Known structures in the PDB
PDB ID1NYO
Total residue count163
Number of chains1
MethodNMR
ResolutionN/A
1 20 39 58 77 96 115 134 153 172 191 Range: 68 to 191  |  Coverage: 63% Fasciclin Range: 31 to 193  |  Coverage: 83% 1 Range: 31 to 193  |  Coverage: 83% 1
Number of amino acids : 193
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
FasciclinPF0246968-191
Mtb Structural Proteome models
Model Number1
Model nameRv2875
Template1NYO    APDBCREDO
Template coverage1_163
Template Identity(%)100.0
Model coverage(%)83.9
Normalized DOPE score-1.631

Structure Models from Chopin
Model Number1
Profileb.118.1.1 - 2.30.180.10
Click for model details
zscore25.77
Residue begin31
Residue end193
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2875Gene nameConfidence Score
Rv2876Rv28760.943
Rv0445csigK0.934
Rv0445csigK0.934
Rv2874dipZ0.926
Rv2874dipZ0.926
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions