Rv2842c

Tuberculist information
Gene nameRv2842c
Protein functionConserved protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)3149.43
Molecular mass(da)19533.3
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 183
	  		  	1    VTTGLPSQRQVIELLGADFACAGYEIEDVVIDARARPPRIAVIADGDAPLDLDTIAALSR   60
			  	61   RASALLDGLDGANKIRGRYLLEVSSPGVERPLTSEKHFRRARGRKVELVLSDGSRLTGRV  120
			  	121  GEMRAGTVALVIREDRGWAVREIPLAEIVKAVVQVEFSPPAPAELELAQSSEMGLARGTE  180
			  	181  AGA

Known structures in the PDB
No Known structures
1 19 37 55 73 91 109 127 145 163 181 Range: 14 to 153  |  Coverage: 75% DUF150 Range: 8 to 156  |  Coverage: 80% 1 Range: 1 to 159  |  Coverage: 86% 1 Range: 3 to 86  |  Coverage: 45% 2 Range: 90 to 159  |  Coverage: 37% 3
Number of amino acids : 183
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
DUF150PF0257614-153
Mtb Structural Proteome models
Model Number1
Model nameRv2842c
Template1IB8    APDBCREDO
Template coverage11_161
Template Identity(%)20.1
Model coverage(%)80.9
Normalized DOPE score0.378

Structure Models from Chopin
Model Number1
Profileb.38.2.1, d.52.4.1 - 2.30.30.180, 3.30.300.70
Click for model details
zscore25.35
Residue begin1
Residue end159
Model Number2
Profile3.30.300.70
Click for model details
zscore16.91
Residue begin3
Residue end86
Model Number3
Profileb.38.2.1
Click for model details
zscore14.7
Residue begin90
Residue end159
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2842cGene nameConfidence Score
Rv2841cnusA0.982
Rv2841cnusA0.982
Rv2839cinfB0.937
Rv2839cinfB0.937
Rv2839cinfB0.937
Rv2839cinfB0.937
Rv2793ctruB0.934
Rv2793ctruB0.934
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions