Rv2610c

Tuberculist information
Gene namepimA
Protein functionAlpha-mannosyltransferase PimA
Functional category(tuberculist)lipid metabolism
Gene location(kb)2937.86
Molecular mass(da)40445.5
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 378
	  		  	1    MRIGMICPYSFDVPGGVQSHVLQLAEVMRTRGHLVSVLAPASPHAALPDYFVSGGRAVPI   60
			  	61   PYNGSVARLRFGPATHRKVKKWLAHGDFDVLHLHEPNAPSLSMLALNIAEGPIVATFHTS  120
			  	121  TTKSLTLTVFQGILRPMHEKIVGRIAVSDLARRWQMEALGSDAVEIPNGVDVDSFASAAR  180
			  	181  LDGYPRQGKTVLFLGRYDEPRKGMAVLLDALPKVVQRFPDVQLLIVGHGDADQLRGQAGR  240
			  	241  LAAHLRFLGQVDDAGKASAMRSADVYCAPNTGGESFGIVLVEAMAAGTAVVASDLDAFRR  300
			  	301  VLRDGEVGHLVPVDPPDLQAAALADGLIAVLENDVLRERYVAAGNAAVRRYDWSVVASQI  360
			  	361  MRVYETVAGSGAKVQVAS

Known structures in the PDB
No Known structures
1 38 75 112 149 186 223 260 297 334 371 Range: 4 to 176  |  Coverage: 45% Glyco_transf_4 Range: 181 to 347  |  Coverage: 43% Glycos_transf_1 Range: 2 to 375  |  Coverage: 98% 1 Range: 1 to 370  |  Coverage: 97% 1
Number of amino acids : 378
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Glyco_transf_4PF134394-176
Glycos_transf_1PF00534181-347
Mtb Structural Proteome models
Model Number1
Model nameRv2610c
Template1V4V    APDBCREDO
Template coverage7_372
Template Identity(%)14.5
Model coverage(%)98.7
Normalized DOPE score0.17

Structure Models from Chopin
Model Number1
Profilec.87.1.8
Click for model details
zscore35.17
Residue begin1
Residue end370
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2610cGene nameConfidence Score
Rv2611cRv2611c0.992
Rv2609cRv2609c0.977
Rv2612cpgsA10.971
Rv2613cRv2613c0.968
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
GDP-mannosePubChem0.833605.341