Rv2366c

Tuberculist information
Gene nameRv2366c
Protein functionProbable conserved transmembrane protein
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)2647.06
Molecular mass(da)47195.2
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 435
	  		  	1    LTGYYQLLGSIVLIGLGGLFAAIDAAISTVSPARVDELVRDQRPGAGSLRKVMADRPRYV   60
			  	61   NLVVLLRTSCEITATALLVVFIRYHFSMVWGLYLAAGIMVLASFVVVGVGPRTLGRQNAY  120
			  	121  SISLATALPLRLISWLLMPISRLLVLLGNALTPGRGFRNGPFASEIELREVVDLAQQRGV  180
			  	181  VAADERRMIESVFELGDTPAREVMVPRTEMIWIESDKTAGQAMTLAVRSGHSRIPVIGEN  240
			  	241  VDDIVGVVYLKDLVEQTFCSTNGGRETTVARVMRPAVFVPDSKPLDALLREMQRDRNHMA  300
			  	301  LLVDEYGAIAGLVSIEDVLEEIVGEIADEYDQAETAPVEDLGDKRFRVSARLPIEDVGEL  360
			  	361  YGVEFDDDLDVDTVGGLLALELGRVPLPGAEVISHGLRLHAEGGTDHRGRVRIGTVLLSP  420
			  	421  AEPDGADDEEADHPG

Known structures in the PDB
No Known structures
1 44 87 130 173 216 259 302 345 388 431 Range: 5 to 185  |  Coverage: 41% DUF21 Range: 200 to 256  |  Coverage: 12% CBS Range: 269 to 324  |  Coverage: 12% CBS Range: 339 to 421  |  Coverage: 18% CorC_HlyC Range: 198 to 326  |  Coverage: 29% 1 Range: 339 to 421  |  Coverage: 18% 1
Number of amino acids : 435
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
DUF21PF015955-185
CBSPF00571200-256
CBSPF00571269-324
CorC_HlyCPF03471339-421
Mtb Structural Proteome models
Model Number1
Model nameRv2366c
Template1VR9    APDBCREDO
Template coverage1_120
Template Identity(%)18.3
Model coverage(%)29.4
Normalized DOPE score-0.923

Structure Models from Chopin
Model Number1
Profiled.145.1.4 - 3.30.465.10
Click for model details
zscore11.96
Residue begin339
Residue end421
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2366cGene nameConfidence Score
Rv2368cphoH10.984
Rv2368cphoH10.984
Rv2367cRv2367c0.982
Rv2364cera0.915
Rv2364cera0.915
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
selenomethioninePubChem0.796196.106
SeMetPubChem0.796196.106