Rv2174

Tuberculist information
Gene namemptA
Protein functionAlpha(1->6)mannosyltransferase. Possible conserved integral membrane protein.
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)2435.91
Molecular mass(da)55293.7
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 516
	  		  	1    MTTPSHAPAVDLATAKDAVVQHLSRLFEFTTGPQGGPARLGFAGAVLITAGGLGAGSVRQ   60
			  	61   HDPLLESIHMSWLRFGHGLVLSSILLWTGVGVMLLAWLGLGRRVLAGEATEFTMRATTVI  120
			  	121  WLAPLLLSVPVFSRDTYSYLAQGALLRDGLDPYAVGPVGNPNALLDDVSPIWTITTAPYG  180
			  	181  PAFILVAKFVTVIVGNNVVAGTMLLRLCMLPGLALLVWATPRLASHLGTHGPTALWICVL  240
			  	241  NPLVLIHLMGGVHNEMLMVGLMTAGIALTVQGRNVAGIILITVAIAVKATAGIALPFLVW  300
			  	301  VWLRHLRERRGYRPVQAFLAAAAISLLIFVAVFAVLSAVAGVGLGWLTALAGSVKIINWL  360
			  	361  TVPTGAANVIHALGRGLFTVDFYTLLRITRLIGIVIIAVSLPLLWWRFRRDDRAALTGVA  420
			  	421  WSMLIVVLFVPAALPWYYSWPLAVAAPLAQARRAIAAIAGLSTWVMVIFKPDGSHGMYSW  480
			  	481  LHFWIATACALTAWYVLYRSPDRRGVQAATPVVNTP

Known structures in the PDB
No Known structures
1 52 103 154 205 256 307 358 409 460 511 Range: 159 to 299  |  Coverage: 27% PMT_2
Number of amino acids : 516
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
PMT_2PF13231159-299
Mtb Structural Proteome models
Structure models not available for this query
Structure Models from Chopin
CHOPIN models not available for this query
Binding pockets
Structure models not available for this query
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2174Gene nameConfidence Score
Rv2173idsA20.976
Rv2181Rv21810.901
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions