Rv2149c

Tuberculist information
Gene nameyfiH
Protein functionConserved protein YfiH
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)2407.62
Molecular mass(da)25946.5
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 250
	  		  	1    LLASTRHIARGDTGNVSVRIRRVTTTRAGGVSAPPFDTFNLGDHVGDDPAAVAANRARLA   60
			  	61   AAIGLPGNRVVWMNQVHGDRVELVDQPRNTALDDTDGLVTATPRLALAVVTADCVPVLMA  120
			  	121  DARAGIAAAVHAGRAGAQRGVVVRALEVMLSLGAQVRDISALLGPAVSGRNYEVPAAMAD  180
			  	181  EVEAALPGSRTTTAAGTPGVDLRAGIACQLRDLGVESIDVDPRCTVADPTLFSHRRDAPT  240
			  	241  GRFASLVWME

Known structures in the PDB
No Known structures
1 26 51 76 101 126 151 176 201 226 251 Range: 24 to 249  |  Coverage: 90% Cu-oxidase_4 Range: 16 to 250  |  Coverage: 93% 1 Range: 1 to 250  |  Coverage: 99% 1
Number of amino acids : 250
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Cu-oxidase_4PF0257824-249
Mtb Structural Proteome models
Model Number1
Model nameRv2149c
Template1RV9    APDBCREDO
Template coverage24_255
Template Identity(%)36.2
Model coverage(%)93.6
Normalized DOPE score-0.448

Structure Models from Chopin
Model Number1
Profiled.194.1.2 - 3.60.140.10
Click for model details
zscore44.58
Residue begin1
Residue end250
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2149cGene nameConfidence Score
Rv2147cRv2147c0.983
Rv2148cRv2148c0.981
Rv2150cftsZ0.975
Rv2150cftsZ0.975
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
selenomethioninePubChem0.772196.106
hydride acetatePubChem0.77261.0599
glycerolPubChem0.77292.0938
SeMetPubChem0.772196.106
acetatePubChem0.77259.044