Rv2148c

Tuberculist information
Gene nameRv2148c
Protein functionConserved protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)2406.84
Molecular mass(da)27693.4
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 258
	  		  	1    MAADLSAYPDRESELTHALAAMRSRLAAAAEAAGRNVGEIELLPITKFFPATDVAILFRL   60
			  	61   GCRSVGESREQEASAKMAELNRLLAAAELGHSGGVHWHMVGRIQRNKAGSLARWAHTAHS  120
			  	121  VDSSRLVTALDRAVVAALAEHRRGERLRVYVQVSLDGDGSRGGVDSTTPGAVDRICAQVQ  180
			  	181  ESEGLELVGLMGIPPLDWDPDEAFDRLQSEHNRVRAMFPHAIGLSAGMSNDLEVAVKHGS  240
			  	241  TCVRVGTALLGPRRLRSP

Known structures in the PDB
No Known structures
1 26 51 76 101 126 151 176 201 226 251 Range: 17 to 254  |  Coverage: 91% Ala_racemase_N Range: 14 to 252  |  Coverage: 92% 1 Range: 1 to 258  |  Coverage: 99% 1
Number of amino acids : 258
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Ala_racemase_NPF0116817-254
Mtb Structural Proteome models
Model Number1
Model nameRv2148c
Template1W8G    APDBCREDO
Template coverage3_228
Template Identity(%)33.6
Model coverage(%)92.2
Normalized DOPE score-0.503

Structure Models from Chopin
Model Number1
Profilec.1.6.2 - 3.20.20.10
Click for model details
zscore18.13
Residue begin1
Residue end258
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2148cGene nameConfidence Score
Rv2149cyfiH0.981
Rv2150cftsZ0.968
Rv2150cftsZ0.968
Rv2147cRv2147c0.944
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
pyridoxal phosphatePubChem0.864247.142