Rv2131c

Tuberculist information
Gene namecysQ
Protein functionMonophosphatase CysQ
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)2392.52
Molecular mass(da)28415.1
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 267
	  		  	1    VVSPAAPDLTDDLTDAELAADLAADAGKLLLQVRAEIGFDQPWTLGEAGDRQANSLLLRR   60
			  	61   LQAERPGDAVLSEEAHDDLARLKSDRVWIIDPLDGTREFSTPGRDDWAVHIALWRRSSNG  120
			  	121  QPEITDAAVALPARGNVVYRTDTVTSGAAPAGVPGTLRIAVSATRPPAVLHRIRQTLAIQ  180
			  	181  PVSIGSAGAKAMAVIDGYVDAYLHAGGQWEWDSAAPAGVMLAAGMHASRLDGSPLRYNQL  240
			  	241  DPYLPDLLMCRAEVAPILLGAIADAWR

Known structures in the PDB
No Known structures
1 27 53 79 105 131 157 183 209 235 261 Range: 11 to 266  |  Coverage: 95% Inositol_P Range: 11 to 263  |  Coverage: 94% 1 Range: 1 to 267  |  Coverage: 99% 1 Range: 1 to 182  |  Coverage: 67% 2
Number of amino acids : 267
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Inositol_PPF0045911-266
Mtb Structural Proteome models
Model Number1
Model nameRv2131c
Template1LBV    APDBCREDO
Template coverage2_252
Template Identity(%)23.5
Model coverage(%)94.0
Normalized DOPE score0.148

Structure Models from Chopin
Model Number1
Profilee.7.1.1
Click for model details
zscore22.82
Residue begin1
Residue end267
Model Number2
Profile3.30.540.10
Click for model details
zscore10.22
Residue begin1
Residue end182
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2131cGene nameConfidence Score
Rv1286cysN0.994
Rv1286cysN0.994
Rv1286cysN0.994
Rv1285cysD0.98
Rv1604impA0.911
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions