Rv2030c

Tuberculist information
Gene nameRv2030c
Protein functionConserved protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)2276.44
Molecular mass(da)74898.2
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 681
	  		  	1    VLMTAAADVTRRSPRRVFRDRREAGRVLAELLAAYRDQPDVIVLGLARGGLPVAWEVAAA   60
			  	61   LHAPLDAFVVRKLGAPGHDEFAVGALASGGRVVVNDDVVRGLRITPQQLRDIAEREGREL  120
			  	121  LRRESAYRGERPPTDITGKTVIVVDDGLATGASMFAAVQALRDAQPAQIVIAVPAAPEST  180
			  	181  CREFAGLVDDVVCATMPTPFLAVGESFWDFRQVTDEEVRRLLATPTAGPSLRRPAASTAA  240
			  	241  DVLRRVAIDAPGGVPTHEVLAELVGDARIVLIGESSHGTHEFYQARAAMTQWLIEEKGFG  300
			  	301  AVAAEADWPDAYRVNRYVRGLGEDTNADEALSGFERFPAWMWRNTVVRDFVEWLRTRNQR  360
			  	361  YESGALRQAGFYGLDLYSLHRSIQEVISYLDKVDPRAAARARARYACFDHACADDGQAYG  420
			  	421  FAAAFGAGPSCEREAVEQLVDVQRNALAYARQDGLLAEDELFYAQQNAQTVRDAEVYYRA  480
			  	481  MFSGRVTSWNLRDQHMAQTLGSLLTHLDRHLDAPPARIVVWAHNSHVGDARATEVWADGQ  540
			  	541  LTLGQIVRERYGDESRSIGFSTYTGTVTAASEWGGIAQRKAVRPALHGSVEELFHQTADS  600
			  	601  FLVSARLSRDAEAPLDVVRLGRAIGVVYLPATERQSHYLHVRPADQFDAMIHIDQTRALE  660
			  	661  PLEVTSRWIAGENPETYPTGL

Known structures in the PDB
No Known structures
1 69 137 205 273 341 409 477 545 613 681 Range: 14 to 175  |  Coverage: 23% Pribosyltran Range: 301 to 656  |  Coverage: 52% Erythro_esteras Range: 17 to 225  |  Coverage: 30% 1 Range: 230 to 663  |  Coverage: 63% 1 Range: 14 to 175  |  Coverage: 23% 2
Number of amino acids : 681
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
PribosyltranPF0015614-175
Erythro_esterasPF05139301-656
Mtb Structural Proteome models
Model Number1
Model nameRv2030c
Template1WD5    APDBCREDO
Template coverage2_206
Template Identity(%)42.4
Model coverage(%)30.5
Normalized DOPE score-1.209

Structure Models from Chopin
Model Number1
Profilec.150.1.3
Click for model details
zscore41.76
Residue begin230
Residue end663
Model Number2
Profilec.61.1.1 - 3.40.50.2020
Click for model details
zscore12.97
Residue begin14
Residue end175
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2030cGene nameConfidence Score
Rv2028cRv2028c0.965
Rv2031chspX0.911
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions