Rv2028c

Tuberculist information
Gene nameRv2028c
Protein functionUniversal stress protein family protein
Functional category(tuberculist)virulence,detoxification and adaptaion
Gene location(kb)2274.57
Molecular mass(da)29441.6
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 279
	  		  	1    MNQSHKPPSIVVGIDGSKPAVQAALWAVDEAASRDIPLRLLYAIEPDDPGYAAHGAAARK   60
			  	61   LAAAENAVRYAFTAVEAADRPVKVEVEITQERPVTSLIRASAAAALVCVGAIGVHHFRPE  120
			  	121  RVGSTAAALALSAQCPVAIVRPHRVPIGRDAAWIVVEADGSSDIGVLLGAVMAEARLRDS  180
			  	181  PVRVVTCRQSGVGDTGDDVRASLDRWLARWQPRYPDVRVQSAAVHGELLDYLAGLGRSVH  240
			  	241  MVVLSASDQEHVEQLVGAPGNAVLQEAGCTLLVVGQQYL

Known structures in the PDB
No Known structures
1 28 55 82 109 136 163 190 217 244 271 Range: 8 to 141  |  Coverage: 47% Usp Range: 7 to 140  |  Coverage: 47% 1 Range: 2 to 154  |  Coverage: 54% 1
Number of amino acids : 279
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
UspPF005828-141
Mtb Structural Proteome models
Model Number1
Model nameRv2028c
Template1WJG    APDBCREDO
Template coverage2_136
Template Identity(%)23.1
Model coverage(%)47.7
Normalized DOPE score-0.27

Structure Models from Chopin
Model Number1
Profilec.26.2.4 - 3.40.50.620
Click for model details
zscore10.01
Residue begin2
Residue end154
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2028cGene nameConfidence Score
Rv2030cRv2030c0.965
Rv2030cRv2030c0.965
Rv2029cpfkB0.933
Rv2031chspX0.922
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions