Rv1897c

Tuberculist information
Gene nameRv1897c
Protein functionConserved hypothetical protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)2144.45
Molecular mass(da)15084.4
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 143
	  		  	1    VRVLVQRVSSAAVRVDGRVVGAIRPDGQGLVAFVGVTHGDDLDKARRLAEKLWNLRVLAD   60
			  	61   EKSASDMHAPILVISQFTLYADTAKGRRPSWNAAAPGAVAQPLIAAFAAALRQLGAHVEA  120
			  	121  GVFGAHMQVELVNDGPVTVMLEG

Known structures in the PDB
No Known structures
1 15 29 43 57 71 85 99 113 127 141 Range: 2 to 143  |  Coverage: 98% Tyr_Deacylase Range: 1 to 143  |  Coverage: 99% 1 Range: 1 to 143  |  Coverage: 99% 1
Number of amino acids : 143
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Tyr_DeacylasePF025802-143
Mtb Structural Proteome models
Model Number1
Model nameRv1897c
Template2DBO    APDBCREDO
Template coverage1_145
Template Identity(%)44.1
Model coverage(%)99.3
Normalized DOPE score-0.887

Structure Models from Chopin
Model Number1
Profilec.110.1.1 - 3.50.80.10
Click for model details
zscore28.12
Residue begin1
Residue end143
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1897cGene nameConfidence Score
Rv2220glnA10.904
Rv2220glnA10.904
Rv2583crelA0.901
Rv2583crelA0.901
Rv2583crelA0.901
Rv2583crelA0.901
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
deoxythymidine diphosphate-glucosePubChem0.77564.329
dTDP-glucosePubChem0.768564.329
L-rhamnosePubChem0.767164.156
3,3'-dithiodipropionic acidPubChem0.762210.271
dTDP-L-rhamnosePubChem0.762548.33
thymidylatePubChem0.744322.208
gamma-mercaptobutyric acidPubChem0.741120.17
D-serinePubChem0.736105.093
3,3'-thiodipropionic acidPubChem0.735178.206
glucose-1-phosphatePubChem0.731260.136
L-histidinePubChem0.728155.155
rhamnosePubChem0.723164.156
L-serinePubChem0.721105.093
fucosePubChem0.709164.156
zincPubChem0.70265.409
dADPPubChem0.7411.202