SInCRe - Rv1716

Tuberculist information

Gene name	Rv1716
Protein function	Conserved hypothetical protein
Functional category(tuberculist)	conserved hypotheticals
Gene location(kb)	1943.58
Molecular mass(da)	30073
External sites	TB Database TubercuList WebTB

Protein sequence

Number of amino acids : 276

	  		  	1    MTFAWPLGAAESTLEFYDLSHPWGHGAPAWPYFEDVQIERLHGMAKSRVLTQKITTVMHS   60
			  	61   GTHIDAPAHVVEGTPFLDEIPLSAFFGTGVVVSIPKGKWGMVTAEDLQNATPDIRPGDIV  120
			  	121  VVNTGWHHKYADSAEYYAYSPGFDKKAGEWFAAKGVKAVGTDTQALDHPLATAIAPHSPA  180
			  	181  EAQGGLLPWAVREYEAQTGRKVLDDFPDWEPCHRAILSQGIYGFENVGGDLDKVTGKRVT  240
			  	241  FAAFPWRWVGGDGCIVRLVAIVDPTGSYRIETGKAV

Known structures in the PDB

No Known structures

Number of amino acids : 276

Domains assigned based on sequence.

Mtb Structural proteome models

CHOPIN models

Profile-based domain assignment

Structural/Functional domain family	Pfam acc.no./SCOP ID	Domain Region
Cyclase	PF04199	16-170

Mtb Structural Proteome models

Model Number	1
Model name	Rv1716
Template	1R61 APDB CREDO
Template coverage	-1_201
Template Identity(%)	26.1
Model coverage(%)	90.2
Normalized DOPE score	0.816

Structure Models from Chopin

Model Number	1
Profile	c.8.8.1 - 3.50.30.50 Click for model details
zscore	38.03
Residue begin	12
Residue end	263

Binding pockets

STRING

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Protein interacting with Rv1716	Gene name	Confidence Score
Rv1717	Rv1717	0.978
Rv1714	Rv1714	0.953
Rv1715	fadB3	0.932
Rv1715	fadB3	0.932

Potential ligand/drug binding sites

No binding sites identified

Similarity to known drug target from sensitive sequence analysis

No drug targets

List of small molecules tested from TIBLE

Data not available

Off-target activity - ligand based from TIBLE

Data not available

Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.

Data not available

STITCH interactions

No high confidence interactions