Rv1714

Tuberculist information
Gene nameRv1714
Protein functionProbable oxidoreductase
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)1941.85
Molecular mass(da)27953.8
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 270
	  		  	1    VEEMALAQQVPNLGLARFSVQDKSILITGATGSLGRVAARALADAGARLTLAGGNSAGLA   60
			  	61   ELVNGAGIDDAAVVTCRPDSLADAQQMVEAALGRYGRLDGVLVASGSNHVAPITEMAVED  120
			  	121  FDAVMDANVRGAWLVCRAAGRVLLEQGQGGSVVLVSSVRGGLGNAAGYSAYCPSKAGTDL  180
			  	181  LAKTLAAEWGGHGIRVNALAPTVFRSAVTEWMFTDDPKGRATREAMLARIPLRRFAEPED  240
			  	241  FVGALIYLLSDASSFYTGQVMYLDGGYTAC

Known structures in the PDB
No Known structures
1 28 55 82 109 136 163 190 217 244 271 Range: 23 to 190  |  Coverage: 61% adh_short Range: 18 to 269  |  Coverage: 92% 1 Range: 1 to 270  |  Coverage: 99% 1
Number of amino acids : 270
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
adh_shortPF0010623-190
Mtb Structural Proteome models
Model Number1
Model nameRv1714
Template1VL8    APDBCREDO
Template coverage5_254
Template Identity(%)33.6
Model coverage(%)93.0
Normalized DOPE score-0.595

Structure Models from Chopin
Model Number1
Profilec.2.1.2 - 3.40.50.720
Click for model details
zscore23.6
Residue begin1
Residue end270
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1714Gene nameConfidence Score
Rv1717Rv17170.966
Rv1716Rv17160.953
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions