Rv1677

Tuberculist information
Gene namedsbF
Protein functionProbable conserved lipoprotein DsbF
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)1901.75
Molecular mass(da)19205.8
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 182
	  		  	1    VTHSRLIGALTVVAIIVTACGSQPKSQPAVAPTGDAAAATQVPAGQTVPAQLQFSAKTLD   60
			  	61   GHDFHGESLLGKPAVLWFWAPWCPTCQGEAPVVGQVAASHPEVTFVGVAGLDQVPAMQEF  120
			  	121  VNKYPVKTFTQLADTDGSVWANFGVTQQPAYAFVDPHGNVDVVRGRMSQDELTRRVTALT  180
			  	181  SR

Known structures in the PDB
PDB ID1ZZO
Total residue count136
Number of chains1
MethodX-RAY
Resolution1.6
PDB ID3IOS
Total residue count150
Number of chains1
MethodX-RAY
Resolution1.6
1 19 37 55 73 91 109 127 145 163 181 Range: 41 to 178  |  Coverage: 75% Redoxin Range: 45 to 178  |  Coverage: 73% 1 Range: 47 to 180  |  Coverage: 73% 2 Range: 28 to 182  |  Coverage: 84% 1
Number of amino acids : 182
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
RedoxinPF0853441-178
Mtb Structural Proteome models
Model Number1
Model nameRv1677_3ios_A
Template3IOS    APDBCREDO
Template coverage45_178
Template Identity(%)100.0
Model coverage(%)73.1
Normalized DOPE score-2.857

Model Number2
Model nameRv1677
Template1ZZO    APDBCREDO
Template coverage45_178
Template Identity(%)100.0
Model coverage(%)73.1
Normalized DOPE score-2.63

Structure Models from Chopin
Model Number1
Profilec.47.1.20
Click for model details
zscore10.49
Residue begin28
Residue end182
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1677Gene nameConfidence Score
Rv1676Rv16760.977
Rv0527ccdA0.944
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions