Rv1551

Tuberculist information
Gene nameplsB1
Protein functionPossible acyltransferase PlsB1
Functional category(tuberculist)lipid metabolism
Gene location(kb)1755.44
Molecular mass(da)69192
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 621
	  		  	1    VTAREVGRIGLRKLLQRIGIVAESMTPLATDPVEVTQLLDARWYDERLRALADELGRDPD   60
			  	61   SVRAEAAGYLREMAASLDERAVQAWRGFSRWLMRAYDVLVDEDQITQLRKLDRKATLAFA  120
			  	121  FSHRSYLDGMLLPEAILANRLSPALTFGGANLNFFPMGAWAKRTGAIFIRRQTKDIPVYR  180
			  	181  FVLRAYAAQLVQNHVNLTWSIEGGRTRTGKLRPPVFGILRYITDAVDEIDGPEVYLVPTS  240
			  	241  IVYDQLHEVEAMTTEAYGAVKRPEDLRFLVRLARQQGERLGRAYLDFGEPLPLRKRLQEM  300
			  	301  RADKSGTGSEIERIALDVEHRINRATPVTPTAVVSLALLGADRSLSISEVLATVRPLASY  360
			  	361  IAARNWAVAGAADLTNRSTIRWTLHQMVASGVVSVYDAGTEAVWGIGEDQHLVAAFYRNT  420
			  	421  AIHILVDRAVAELALLAAAETTTNGSVSPATVRDEALSLRDLLKFEFLFSGRAQFEKDLA  480
			  	481  NEVLLIGSVVDTSKPAAAADVWRLLESADVLLAHLVLRPFLDAYHIVADRLAAHEDDSFD  540
			  	541  EEGFLAECLQVGKQWELQRNIASAESRSMELFKTALRLARHRELVDGADATDIAKRRQQF  600
			  	601  ADEIATATRRVNTIAELARRQ

Known structures in the PDB
No Known structures
1 63 125 187 249 311 373 435 497 559 621 Range: 103 to 242  |  Coverage: 22% Acyltransferase Range: 10 to 351  |  Coverage: 54% 1 Range: 3 to 349  |  Coverage: 55% 1
Number of amino acids : 621
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
AcyltransferasePF01553103-242
Mtb Structural Proteome models
Model Number1
Model nameRv1551
Template1IUQ    APDBCREDO
Template coverage20_368
Template Identity(%)10.9
Model coverage(%)54.9
Normalized DOPE score0.623

Structure Models from Chopin
Model Number1
Profilec.112.1.1
Click for model details
zscore11.96
Residue begin3
Residue end349
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1551Gene nameConfidence Score
Rv2483cplsC0.989
Rv2483cplsC0.989
Rv2182cRv2182c0.97
Rv1550fadD110.94
Rv2482cplsB20.925
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
glycerol-3-phosphatePubChem0.902172.074
palmitoyl-CoAPubChem0.9021005.94
dihydroxyacetone phosphatePubChem0.902170.058
coenzyme APubChem0.902767.534
palmitoyl dihydroxyacetone phosphatePubChem0.901408.467
1-acyl-sn-glycerol 3-phosphatesPubChem0.9200.084
flavin adenine dinucleotidePubChem0.9785.55
Co-APubChem0.9767.534
Formyl-coenzyme APubChem0.9795.544
FORMYL COENZYME APubChem0.9795.544
palmitatePubChem0.9256.424
palmitoyl CoAPubChem0.91005.94
hexadecanolPubChem0.9242.441