Rv1514c

Tuberculist information
Gene nameRv1514c
Protein functionConserved hypothetical protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)1705.81
Molecular mass(da)28932.8
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 262
	  		  	1    VTSAPTVSVITISFNDLDGLQRTVKSVRAQRYRGRIEHIVIDGGSGDDVVAYLSGCEPGF   60
			  	61   AYWQSEPDGGRYDAMNQGIAHASGDLLWFLHSADRFSGPDVVAQAVEALSGKGPVSELWG  120
			  	121  FGMDRLVGLDRVRGPIPFSLRKFLAGKQVVPHQASFFGSSLVAKIGGYDLDFGIAADQEF  180
			  	181  ILRAALVCEPVTIRCVLCEFDTTGVGSHREPSAVFGDLRRMGDLHRRYPFGGRRISHAYL  240
			  	241  RGREFYAYNSRFWENVFTRMSK

Known structures in the PDB
No Known structures
1 27 53 79 105 131 157 183 209 235 261 Range: 8 to 116  |  Coverage: 41% Glycos_transf_2 Range: 5 to 219  |  Coverage: 81% 1 Range: 5 to 228  |  Coverage: 85% 1
Number of amino acids : 262
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Glycos_transf_2PF005358-116
Mtb Structural Proteome models
Model Number1
Model nameRv1514c
Template1QG8    APDBCREDO
Template coverage2_247
Template Identity(%)19.1
Model coverage(%)81.4
Normalized DOPE score-0.295

Structure Models from Chopin
Model Number1
Profilec.68.1.1 - 3.90.550.10
Click for model details
zscore21.54
Residue begin5
Residue end228
Binding pockets
STRING
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Protein interacting with Rv1514cGene nameConfidence Score
Rv1516cRv1516c0.926
Rv1512epiA0.903
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions