Rv1407

Tuberculist information
Gene namefmu
Protein functionProbable Fmu protein (sun protein)
Functional category(tuberculist)information pathways
Gene location(kb)1583.1
Molecular mass(da)48493.4
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 457
	  		  	1    MTPRSRGPRRRPLDPARRAAFETLRAVSARDAYANLVLPALLAQRGIGGRDAAFATELTY   60
			  	61   GTCRARGLLDAVIGAAAERSPQAIDPVLLDLLRLGTYQLLRTRVDAHAAVSTTVEQAGIE  120
			  	121  FDSARAGFVNGVLRTIAGRDERSWVGELAPDAQNDPIGHAAFVHAHPRWIAQAFADALGA  180
			  	181  AVGELEAVLASDDERPAVHLAARPGVLTAGELARAVRGTVGRYSPFAVYLPRGDPGRLAP  240
			  	241  VRDGQALVQDEGSQLVARALTLAPVDGDTGRWLDLCAGPGGKTALLAGLGLQCAARVTAV  300
			  	301  EPSPHRADLVAQNTRGLPVELLRVDGRHTDLDPGFDRVLVDAPCTGLGALRRRPEARWRR  360
			  	361  QPADVAALAKLQRELLSAAIALTRPGGVVLYATCSPHLAETVGAVADALRRHPVHALDTR  420
			  	421  PLFEPVIAGLGEGPHVQLWPHRHGTDAMFAAALRRLT

Known structures in the PDB
No Known structures
1 46 91 136 181 226 271 316 361 406 451 Range: 14 to 138  |  Coverage: 27% NusB Range: 182 to 454  |  Coverage: 59% Nol1_Nop2_Fmu Range: 14 to 455  |  Coverage: 96% 1 Range: 14 to 455  |  Coverage: 96% 1 Range: 182 to 454  |  Coverage: 59% 2 Range: 1 to 457  |  Coverage: 99% 3 Range: 14 to 156  |  Coverage: 31% 4 Range: 196 to 247  |  Coverage: 11% 5
Number of amino acids : 457
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
NusBPF0102914-138
Nol1_Nop2_FmuPF01189182-454
Mtb Structural Proteome models
Model Number1
Model nameRv1407
Template1SQG    APDBCREDO
Template coverage5_428
Template Identity(%)27.4
Model coverage(%)96.5
Normalized DOPE score0.279

Structure Models from Chopin
Model Number1
Profilea.79.1.3, c.66.1.38 - 1.10.287.730, 1.10.940.10, 3.30.70.1170, 3.40.50.150
Click for model details
zscore61.03
Residue begin14
Residue end455
Model Number2
Profilec.66.1.38
Click for model details
zscore45.29
Residue begin182
Residue end454
Model Number3
Profilec.66.1.38
Click for model details
zscore42.63
Residue begin1
Residue end457
Model Number4
Profile1.10.940.10
Click for model details
zscore29.52
Residue begin14
Residue end156
Model Number5
Profile3.30.70.1170
Click for model details
zscore10.09
Residue begin196
Residue end247
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1407Gene nameConfidence Score
Rv1406fmt0.996
Rv1406fmt0.996
Rv1408rpe0.95
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
S-adenosyl-L-methioninePubChem0.717399.445