Rv1359

Tuberculist information
Gene nameRv1359
Protein functionProbable transcriptional regulatory protein
Functional category(tuberculist)regulatory proteins
Gene location(kb)1530.17
Molecular mass(da)26886.2
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 250
	  		  	1    MFMALRAPMLERMNGLHTDDAPVNWLERRGGRLTSRRRVTLLHAGVEHPMRLWGVQSEAI   60
			  	61   TAAMVLSRKVSAIIAGHCGVRLVDQGVGDGFVAAFAHASDAVACALELHQAPLSPIVLRI  120
			  	121  GIHTGEAQLVDERIYAGATMNLAAELRDLAHGGQTVMSGATEDAVLGRLPMRAWLIGLRP  180
			  	181  MEGSPEGHNFPQSQRIAQLCHPNLRNTFPPLRMRIADASGIPYVGRILVNVQVVPHWEGG  240
			  	241  CAAAGMVLAG

Known structures in the PDB
No Known structures
1 26 51 76 101 126 151 176 201 226 251 Range: 34 to 166  |  Coverage: 52% Guanylate_cyc Range: 34 to 198  |  Coverage: 65% 1 Range: 1 to 218  |  Coverage: 86% 1
Number of amino acids : 250
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Guanylate_cycPF0021134-166
Mtb Structural Proteome models
Model Number1
Model nameRv1359
Template1YBT    APDBCREDO
Template coverage291_455
Template Identity(%)24.2
Model coverage(%)65.6
Normalized DOPE score-0.217

Structure Models from Chopin
Model Number1
Profiled.58.29.1 - 3.30.70.1230
Click for model details
zscore9.86
Residue begin1
Residue end218
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1359Gene nameConfidence Score
Rv1647Rv16470.941
Rv1264Rv12640.92
Rv1120cRv1120c0.902
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions