Rv1344

Tuberculist information
Gene namembtL
Protein functionAcyl carrier protein (ACP) MbtL
Functional category(tuberculist)lipid metabolism
Gene location(kb)1508.97
Molecular mass(da)11400
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 106
	  		  	1    MWRYPLSTRLALPNTPGVASFAMTSSPSTVSTTLLSILRDDLNIDLTRVTPDARLVDDVG   60
			  	61   LDSVAFAVGMVAIEERLGVALSEEELLTCDTVGELEAAIAAKYRDE

Known structures in the PDB
No Known structures
1 11 21 31 41 51 61 71 81 91 101 Range: 32 to 99  |  Coverage: 63% PP-binding Range: 23 to 106  |  Coverage: 78% 1 Range: 21 to 106  |  Coverage: 80% 1
Number of amino acids : 106
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
PP-bindingPF0055032-99
Mtb Structural Proteome models
Model Number1
Model nameRv1344
Template1KLP    APDBCREDO
Template coverage1_83
Template Identity(%)27.7
Model coverage(%)78.3
Normalized DOPE score-0.842

Structure Models from Chopin
Model Number1
Profilea.28.1.1 - 1.10.1200.10
Click for model details
zscore13.88
Residue begin21
Residue end106
Binding pockets
STRING
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Protein interacting with Rv1344Gene nameConfidence Score
Rv1345mbtM0.979
Rv1346mbtN0.977
Rv1346mbtN0.977
Rv1346mbtN0.977
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions