Rv1335

Tuberculist information
Gene namecysO
Protein functionSulfur carrier protein CysO
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)1503.1
Molecular mass(da)9556.7
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 93
	  		  	1    MNVTVSIPTILRPHTGGQKSVSASGDTLGAVISDLEANYSGISERLMDPSSPGKLHRFVN   60
			  	61   IYVNDEDVRFSGGLATAIADGDSVTILPAVAGG

Known structures in the PDB
PDB ID3DWG
Total residue count743
Number of chains3
MethodX-RAY
Resolution1.53
PDB ID3DWM
Total residue count186
Number of chains2
MethodX-RAY
Resolution2.69
1 10 19 28 37 46 55 64 73 82 91 Range: 5 to 93  |  Coverage: 94% ThiS Range: 2 to 93  |  Coverage: 97% 1 Range: 4 to 93  |  Coverage: 95% 2 Range: to 1  |  Coverage: 1% 3 Range: 1 to 93  |  Coverage: 98% 1
Number of amino acids : 93
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
ThiSPF025975-93
Mtb Structural Proteome models
Model Number1
Model nameRv1335_3dwg_C
Template3DWG    CPDBCREDO
Template coverage2_93
Template Identity(%)100.0
Model coverage(%)97.8
Normalized DOPE score-2.25

Model Number2
Model nameRv1335
Template1V8C    APDBCREDO
Template coverage2_87
Template Identity(%)30.2
Model coverage(%)95.7
Normalized DOPE score-1.551

Model Number3
Model nameRv1335_3dwg_B
Template3DWG    BPDBCREDO
Template coverage0_323
Template Identity(%)100.0
Model coverage(%)347.3
Normalized DOPE score-1.241

Structure Models from Chopin
Model Number1
Profiled.15.3.3 - 3.10.20.30
Click for model details
zscore13.41
Residue begin1
Residue end93
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1335Gene nameConfidence Score
Rv1334mec0.999
Rv1336cysM0.999
Rv3206cmoeB10.997
Rv3206cmoeB10.997
Rv3206cmoeB10.997
Rv3116moeB20.962
Rv3116moeB20.962
Rv3116moeB20.962
Rv2334cysK10.945
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
pyridoxal phosphatePubChem0.9247.142