SInCRe - Rv1301

Tuberculist information

Gene name	Rv1301
Protein function	Conserved protein
Functional category(tuberculist)	conserved hypotheticals
Gene location(kb)	1457.56
Molecular mass(da)	22552.7
External sites	TB Database TubercuList WebTB

Protein sequence

Number of amino acids : 217

	  		  	1    LTETFDCADPEQRSRGIVSAVGAIKAGQLVVMPTDTVYGIGADAFDSSAVAALLSAKGRG   60
			  	61   RDMPVGVLVGSWHTIEGLVYSMPDGARELIRAFWPGALSLVVVQAPSLQWDLGDAHGTVM  120
			  	121  LRMPLHPVAIELLREVGPMAVSSANISGHPPPVDAEQARSQLGDHVAVYLDAGPSEQQAG  180
			  	181  STIVDLTGATPRVLRPGPVSTERIAEVLGVDAASLFG

Known structures in the PDB

No Known structures

Number of amino acids : 217

Domains assigned based on sequence.

Mtb Structural proteome models

CHOPIN models

Profile-based domain assignment

Structural/Functional domain family	Pfam acc.no./SCOP ID	Domain Region
Sua5_yciO_yrdC	PF01300	22-197

Mtb Structural Proteome models

Model Number	1
Model name	Rv1301
Template	1K7J APDB CREDO
Template coverage	1_203
Template Identity(%)	23.3
Model coverage(%)	92.6
Normalized DOPE score	-1.235

Structure Models from Chopin

Model Number	1
Profile	d.115.1.1 - 3.90.870.10 Click for model details
zscore	45.1
Residue begin	1
Residue end	212

Binding pockets

STRING

Cytoscape Web will replace the contents of this div with protein-protein interaction network.

Protein interacting with Rv1301	Gene name	Confidence Score
Rv1300	hemK	0.976
Rv1299	prfA	0.963
Rv1299	prfA	0.963

Potential ligand/drug binding sites

No binding sites identified

Similarity to known drug target from sensitive sequence analysis

No drug targets

List of small molecules tested from TIBLE

Data not available

Off-target activity - ligand based from TIBLE

Data not available

Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.

Data not available

STITCH interactions

Chemical Name	Confidence score	Molecular Weight
selenomethioninePubChem	0.792	196.106
SeMetPubChem	0.792	196.106