Rv1008

Tuberculist information
Gene nametatD
Protein functionProbable deoxyribonuclease TatD (YJJV protein)
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)1127.09
Molecular mass(da)29065.1
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 264
	  		  	1    LVDAHTHLDACGARDADTVRSLVERAAAAGVTAVVTVADDLESARWVTRAAEWDRRVYAA   60
			  	61   VALHPTRADALTDAARAELERLVAHPRVVAVGETGIDMYWPGRLDGCAEPHVQREAFAWH  120
			  	121  IDLAKRTGKPLMIHNRQADRDVLDVLRAEGAPDTVILHCFSSDAAMARTCVDAGWLLSLS  180
			  	181  GTVSFRTARELREAVPLMPVEQLLVETDAPYLTPHPHRGLANEPYCLPYTVRALAELVNR  240
			  	241  RPEEVALITTSNARRAYGLGWMRQ

Known structures in the PDB
No Known structures
1 27 53 79 105 131 157 183 209 235 261 Range: 2 to 258  |  Coverage: 96% TatD_DNase Range: 1 to 263  |  Coverage: 99% 1 Range: 1 to 264  |  Coverage: 99% 1
Number of amino acids : 264
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
TatD_DNasePF010262-258
Mtb Structural Proteome models
Model Number1
Model nameRv1008
Template1YIX    APDBCREDO
Template coverage3_260
Template Identity(%)35.7
Model coverage(%)99.2
Normalized DOPE score-1.024

Structure Models from Chopin
Model Number1
Profilec.1.9.12 - 3.20.20.140
Click for model details
zscore55.86
Residue begin1
Residue end264
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1008Gene nameConfidence Score
Rv2093ctatC0.969
Rv1007cmetS0.966
Rv1010ksgA0.966
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
SeMetPubChem0.783196.106
selenomethioninePubChem0.783196.106
nickelPubChem0.74258.6934
zincPubChem0.73965.409