Rv0992c

Tuberculist information
Gene nameRv0992c
Protein functionConserved hypothetical protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)1108.58
Molecular mass(da)21412.9
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 197
	  		  	1    MAMASKSALRDQLLAARRRVADDVRAAEARMLRGHLERMVTSDSTVCAYVPVGGEPGSIE   60
			  	61   MLDVLLRRAGRVLLPVARTAGGDLPLPLRWGEYRAGGLARARWGLLEPPEPWLPEAALAQ  120
			  	121  ASLVLVPALAVDRQGVRLGRGRGFYDRSLRCRDPHARLVAVVRTVELVDVLPSEPHDVPM  180
			  	181  THALTPERGLIALPCGE

Known structures in the PDB
No Known structures
1 20 39 58 77 96 115 134 153 172 191 Range: 6 to 186  |  Coverage: 91% 5-FTHF_cyc-lig Range: 5 to 193  |  Coverage: 95% 1 Range: 4 to 197  |  Coverage: 97% 1
Number of amino acids : 197
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
5-FTHF_cyc-ligPF018126-186
Mtb Structural Proteome models
Model Number1
Model nameRv0992c
Template1WKC    APDBCREDO
Template coverage2_172
Template Identity(%)39.0
Model coverage(%)95.4
Normalized DOPE score0.456

Structure Models from Chopin
Model Number1
Profilec.124.1.6 - 3.40.50.10420
Click for model details
zscore26.89
Residue begin4
Residue end197
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0992cGene nameConfidence Score
Rv0985cmscL0.924
Rv3356cfolD0.907
Rv3356cfolD0.907
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions