Rv0852

Tuberculist information
Gene namefadD16
Protein functionPossible fatty-acid-CoA ligase FadD16 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)
Functional category(tuberculist)lipid metabolism
Gene location(kb)948.559
Molecular mass(da)30075.9
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 278
	  		  	1    VFTIGYSCASRGADSWLIRRCSVVQGCLDDPGATVEAIDDDGWPHTGDPCSPNSAASGKY   60
			  	61   GERPASVSTGDIHSLVIASDYRVPDPGRVWPLLQRNKSALADIGAHHVLIYASTHDSGRV  120
			  	121  LVMIGVRSREPIVELLRSRVFFDWFDAMGVDDIPAVFAGEIVDRFVAAPTTTQSTPRVPG  180
			  	181  VVVAAFASVNNVSNLTAEVRSAIARFTAAGIRKTWVFQAFDDAHEVLILQEFADEAGARQ  240
			  	241  WIEHPDAAAEWMSGAGVGAYPPLFVGRFFDMMRIEALQ

Known structures in the PDB
No Known structures
1 28 55 82 109 136 163 190 217 244 271 Range: 185 to 250  |  Coverage: 23% 1
Number of amino acids : 278
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Domain assignments not available for this query
Mtb Structural Proteome models
Model Number1
Model nameRv0852
Template1DNY    APDBCREDO
Template coverage8_77
Template Identity(%)15.2
Model coverage(%)23.3
Normalized DOPE score0.828

Structure Models from Chopin
CHOPIN models not available for this query
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0852Gene nameConfidence Score
Rv2831echA160.95
Rv2486echA140.911
Rv1935cechA130.91
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
C0885PubChem0.9917.752
c0682PubChem0.9168.233
C11946PubChem0.9917.752
3-hydroxypropionyl-coenzyme APubChem0.9839.597
trans-2-methyl-5-isopropylhexa-2,5-dienoic acidPubChem0.9168.233
3-hydroxypropionyl-CoAPubChem0.9839.597
C11945PubChem0.9917.752
perillic acidPubChem0.9166.217
(3R)-3-isopropenyl-6-oxoheptanoatePubChem0.9183.224