Rv0649

Tuberculist information
Gene namefabD2
Protein functionPossible malonyl CoA-acyl carrier protein transacylase FabD2 (MCT)
Functional category(tuberculist)lipid metabolism
Gene location(kb)746.363
Molecular mass(da)23616.8
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 224
	  		  	1    MSGRSRLPGSSSRRDAARIVAERVVATVAGVAVAVDEVDAAEARLRDGPRAAALPASGTS   60
			  	61   EGRQLRRWLTQLIVTERVVAAEAAARGLTAAGAPAEADLLPDATARLEIGSVAAAVLADP  120
			  	121  LARALFAAVTARVAVTDDAVADYHARNPLRFAAPCPGQHGWRAPAAAAPPLDQVRRAITE  180
			  	181  HLLGAARRRAFRVWLDARRNALVVLAPGYEHPGDPRQPDNTRRH

Known structures in the PDB
No Known structures
1 23 45 67 89 111 133 155 177 199 221 Range: 23 to 154  |  Coverage: 58% Triger factor/SurA peptide-binding domain-like
Number of amino acids : 224
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Triger factor/SurA peptide-binding domain-likea.223.123-154
Mtb Structural Proteome models
Structure models not available for this query
Structure Models from Chopin
CHOPIN models not available for this query
Binding pockets
Structure models not available for this query
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0649Gene nameConfidence Score
Rv0648Rv06480.966
Rv0648Rv06480.966
Rv0648Rv06480.966
Rv0648Rv06480.966
Rv0904caccD30.922
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
malonyl-CoAPubChem0.947853.58