Rv0574c

Tuberculist information
Gene nameRv0574c
Protein functionConserved hypothetical protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)667.252
Molecular mass(da)41515.3
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 380
	  		  	1    VAGNPDVVTVLLGGDVMLGRGVDQILPHPGKPQLRERYMRDATGYVRLAERVNGRIPLPV   60
			  	61   DWRWPWGEALAVLENTATDVCLINLETTITADGEFADRKPVCYRMHPDNVPALTALRPHV  120
			  	121  CALANNHILDFGYQGLTDTVAALAGAGIQSVGAGADLLAARRSALVTVGHERRVIVGSVA  180
			  	181  AESSGVPESWAARRDRPGVWLIRDPAQRDVADDVAAQVLADKRPGDIAIVSMHWGSNWGY  240
			  	241  ATAPGDVAFAHRLIDAGIDMVHGHSSHHPRPIEIYRGKPILYGCGDVVDDYEGIGGHESF  300
			  	301  RSELRLLYLTVTDPASGNLISLQMLPLRVSRMRLQRASQTDTEWLRNTIERISRRFGIRV  360
			  	361  VTRPDNLLEVVPAANLTSKE

Known structures in the PDB
No Known structures
1 39 77 115 153 191 229 267 305 343 381 Range: 9 to 291  |  Coverage: 74% PGA_cap Range: 46 to 323  |  Coverage: 72% 1 Range: 4 to 370  |  Coverage: 96% 1
Number of amino acids : 380
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
PGA_capPF095879-291
Mtb Structural Proteome models
Model Number1
Model nameRv0574c
Template1T70    APDBCREDO
Template coverage4_248
Template Identity(%)13.5
Model coverage(%)72.9
Normalized DOPE score0.473

Structure Models from Chopin
Model Number1
Profiled.159.1.9 - 3.60.21.30
Click for model details
zscore8.3
Residue begin4
Residue end370
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0574cGene nameConfidence Score
Rv0573cpncB20.93
Rv0575cRv0575c0.909
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions