Rv0575c

Tuberculist information
Gene nameRv0575c
Protein functionPossible oxidoreductase
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)668.579
Molecular mass(da)43366.1
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 388
	  		  	1    VKVAISGAGVAGAALAHWLQRTGHTPTVIERAPKFRTGGYMIDFWGVGYQVAKRMGITDQ   60
			  	61   IAAAGYHMEHVRSVGPTGKVKADLGVDVFRRMVGDDFTSLPRGDLAAAIYTTIEDQVETI  120
			  	121  FDDSIATIDEHRDGVRLTFERTAPRDFDLVIGADGLHSNVRRLVFGPERDFEHYLGCKVA  180
			  	181  ACVVDGYRPRDERSYVLYNTVDRQLARFALRGDRTMFLFVFRAEHDNPGVAPKDELRDQF  240
			  	241  GDVGWESRDILAALDDVEDLYFDVVSQIRMDRWSRGRVLLIGDAAGCISLLGGEGTGLAI  300
			  	301  TEAYVLAGELARAGGDHRRAFDAYEKRLRPFIEGKQASAAKFIWFFATRTRFGLWFRNVA  360
			  	361  MRTMNFGPLATLFAGSVRDDFELPDYTW

Known structures in the PDB
No Known structures
1 39 77 115 153 191 229 267 305 343 381 Range: 1 to 337  |  Coverage: 86% FAD_binding_3 Range: 2 to 373  |  Coverage: 95% 1 Range: 1 to 387  |  Coverage: 99% 1
Number of amino acids : 388
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
FAD_binding_3PF014941-337
Mtb Structural Proteome models
Model Number1
Model nameRv0575c
Template1K0I    APDBCREDO
Template coverage4_363
Template Identity(%)18.6
Model coverage(%)95.6
Normalized DOPE score0.235

Structure Models from Chopin
Model Number1
Profiled.157.1.7 - 3.60.15.10
Click for model details
zscore4.59
Residue begin1
Residue end387
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0575cGene nameConfidence Score
Rv0574cRv0574c0.909
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions