Rv0525

Tuberculist information
Gene nameRv0525
Protein functionConserved protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)616.223
Molecular mass(da)22212.1
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 202
	  		  	1    MPEETQVHVVRHGEVHNPTGILYGRLPGFHLSATGAAQAAAVADALADRDIVAVIASPLQ   60
			  	61   RAQETAAPIAARHDLAVETDPDLIESANFFEGRRVGPGDGAWRDPRVWWQLRNPFTPSWG  120
			  	121  EPYVDIAARMTTAVDKARVRGAGHEVVCVSHQLPVWTLRLYLTGKRLWHDPRRRDCALAS  180
			  	181  VTSLIYDGDRLVDVVYSQPAAL

Known structures in the PDB
No Known structures
1 21 41 61 81 101 121 141 161 181 201 Range: 6 to 158  |  Coverage: 75% His_Phos_1 Range: 4 to 202  |  Coverage: 98% 1 Range: 1 to 202  |  Coverage: 99% 1
Number of amino acids : 202
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
His_Phos_1PF003006-158
Mtb Structural Proteome models
Model Number1
Model nameRv0525
Template1H2E    APDBCREDO
Template coverage2_202
Template Identity(%)23.6
Model coverage(%)98.0
Normalized DOPE score-0.457

Structure Models from Chopin
Model Number1
Profilec.60.1.1 - 3.40.50.1240
Click for model details
zscore30.08
Residue begin1
Residue end202
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0525Gene nameConfidence Score
Rv2135cRv2135c0.966
Rv0524hemL0.907
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions