Rv2135c

Tuberculist information
Gene nameRv2135c
Protein functionConserved protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)2395.3
Molecular mass(da)25122.4
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 236
	  		  	1    MTVILLRHARSTSNTAGVLAGRSGVDLDEKGREQATGLIDRIGDLPIRAVASSPMLRCQR   60
			  	61   TVEPLAEALCLEPLIDDRFSEVDYGEWTGRKIGDLVDEPLWRVVQAHPSAAVFPGGEGLA  120
			  	121  QVQTRAVAAVREHDRRLADQHGHDVLWLACTHGDVIKAVIADAFGMHLDSFQRITADPGS  180
			  	181  VSVVRYTQLRPFVLHVNHTGARLAPALQAAASAQGASPEPNAAVPPGDAVIGGSTD

Known structures in the PDB
No Known structures
1 24 47 70 93 116 139 162 185 208 231 Range: 2 to 159  |  Coverage: 66% His_Phos_1 Range: 2 to 201  |  Coverage: 84% 1 Range: 1 to 236  |  Coverage: 99% 1
Number of amino acids : 236
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
His_Phos_1PF003002-159
Mtb Structural Proteome models
Model Number1
Model nameRv2135c
Template1H2E    APDBCREDO
Template coverage4_201
Template Identity(%)24.2
Model coverage(%)84.3
Normalized DOPE score-0.725

Structure Models from Chopin
Model Number1
Profilec.60.1.1 - 3.40.50.1240
Click for model details
zscore31.15
Residue begin1
Residue end236
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2135cGene nameConfidence Score
Rv0525Rv05250.966
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions