Rv0449c

Tuberculist information
Gene nameRv0449c
Protein functionConserved hypothetical protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)537.229
Molecular mass(da)47784.9
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 439
	  		  	1    VQQSLRRSVAVVGSGVAGLTAAYILSGRDRVTLYEADGRLGGHAHTHYLDNGGGPRGTDV   60
			  	61   VGVDSAFLVHNDRTYPTLCRLFAELGVATQESEMSMSVRADDIGLEYAGALGARGLFACR  120
			  	121  QSLRPRYLCMLAEILRFHRAAARLLREETDNAEDKPETLEAFLSRHHFSQYFVDYFITPL  180
			  	181  VAAVWSCGGADALRYPARYLFVFLDHHGMLSVFGSPTWRTVTGGSANYVQAIAAQLDEVS  240
			  	241  TRTPVHSLRRLPDGVLVGAGDGPSRRFDAAVVAVHPDQALLLLDEPTPAERAVLGAIAYS  300
			  	301  TNSAQLHTDESVLPRHHRARASWNYLVTPGQHQVVVSYDISRLMRLDGGRRYLVTLGGHD  360
			  	361  RVDPSSVIAEMTYSHPLYTPESVAAQRLLPTLGDNRVVFAGAYHGWGFHEDGAASGLRAA  420
			  	421  RRLGADWPAAIPQEAMVAC

Known structures in the PDB
No Known structures
1 44 87 130 173 216 259 302 345 388 431 Range: 16 to 424  |  Coverage: 92% Amino_oxidase Range: 6 to 436  |  Coverage: 97% 1 Range: 1 to 96  |  Coverage: 21% 1
Number of amino acids : 439
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Amino_oxidasePF0159316-424
Mtb Structural Proteome models
Model Number1
Model nameRv0449c
Template1S3E    APDBCREDO
Template coverage4_470
Template Identity(%)17.9
Model coverage(%)97.9
Normalized DOPE score0.703

Structure Models from Chopin
Model Number1
Profilec.5.1.1
Click for model details
zscore4.34
Residue begin1
Residue end96
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0449cGene nameConfidence Score
Rv0448cRv0448c0.999
Rv0447cufaA10.993
Rv0446cRv0446c0.98
Rv0445csigK0.936
Rv0445csigK0.936
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions