Rv0261c

Tuberculist information
Gene namenarK3
Protein functionProbable integral membrane nitrite extrusion protein NarK3 (nitrite facilitator)
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)312.759
Molecular mass(da)49356.5
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 469
	  		  	1    MGRSHQISDWDPEDSVAWEAGNKFIARRNLIWSVAAEHVGFSVWSLWSVMVLFMPTSVYG   60
			  	61   FSAGDKFLLGATATLVGACLRFPYTFATAKFGGRNWTIFSALVLLIPTVGSILLLANPGL  120
			  	121  PLWPYLVCGALAGLGGGNFAASMTNINAFFPQRLKGAALALNAGGGNLGVPMVQLVGLLV  180
			  	181  IATAGDREPYWVCAIYLVLLAVAGLGAALYMDNLTEYRIELNTMRAVVSEPHTWVISLLY  240
			  	241  IGTFGSFIGFSFAFGQVLQINFIASGQSTAQASLHAAQIAFLGPLLGSLSRIYGGKLADR  300
			  	301  IGGGRVTLAAFCAMLLATGILISASTFGDHLAGPMPTATMVGYVIGFTALFILSGIGNGS  360
			  	361  VYKMIPSIFEARSHSLQISEAERRQWSRSMSGALIGLAGAVGALGGVGVNLALRESYLTS  420
			  	421  GTATSAFWAFGVFYLVASVLTWAIYVRRGLKSAGELVPATTAPAGLAYV

Known structures in the PDB
No Known structures
1 47 93 139 185 231 277 323 369 415 461 Range: 38 to 409  |  Coverage: 79% MFS_1 Range: 25 to 453  |  Coverage: 91% 1 Range: to   |  Coverage: 0% 1 Range: to   |  Coverage: 0% 2
Number of amino acids : 469
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
MFS_1PF0769038-409
Mtb Structural Proteome models
Model Number1
Model nameRv0261c
Template2CFQ    APDBCREDO
Template coverage4_408
Template Identity(%)16.8
Model coverage(%)91.3
Normalized DOPE score0.633

Structure Models from Chopin
Model Number1
Profilef.38.1.1
Click for model details
zscore12.1
Residue begin
Residue end
Model Number2
Profilef.38.1.2
Click for model details
zscore5.41
Residue begin
Residue end
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0261cGene nameConfidence Score
Rv1162narH0.953
Rv1162narH0.953
Rv1161narG0.937
Rv1161narG0.937
Rv1161narG0.937
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions