Tuberculist information
Gene nameRv0249c
Protein functionProbable succinate dehydrogenase [membrane anchor subunit] (succinic dehydrogenase)
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)300.834
Molecular mass(da)31077.2
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 273
	  		  	1    MSAPTANRPAIGVFTPTRAQIPERTLRTDLWWLPPLLTNLGLLAFICYATTRAFWGSQYW   60
			  	61   VEKYHYLTPFYSPCVSASCQPGASHLGVWFGHFPGWIPLGAMVLPFLLGFRLTCYYYRKA  120
			  	121  YYRSVWQSPTSCAVPEPRAHYTGETRLPLIVQNTHRYFFYIAVVVSLINTYDAIAAFHSP  180
			  	181  SGFGFGLGNVILTINVVLLWAYTISCHSCRHATGGRLKHFSKHPVRYWIWTQVSKLNTRH  240
			  	241  MQFAWITLGTLALTDFYIMLVASGSITDLRFIG
			  			

Known structures in the PDB
No Known structures
1 28 55 82 109 136 163 190 217 244 271
Profile-based domain assignment
Domain assignments not available for this query
Mtb Structural Proteome models
Structure models not available for this query
Structure Models from Chopin
CHOPIN models not available for this query
Binding pockets
Structure models not available for this query
STRING
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Protein interacting with Rv0249cGene nameConfidence Score
Rv0247cRv0247c0.99
Rv0247cRv0247c0.99
Rv0250cRv0250c0.984
Rv0248cRv0248c0.964
Rv0248cRv0248c0.964
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions