Rv0204c

Tuberculist information
Gene nameRv0204c
Protein functionProbable conserved transmembrane protein
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)241.976
Molecular mass(da)44004.2
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 412
	  		  	1    VSHDAPARNLRQRVGALPRTRVGAPPAEGVPPRGKYWWLRWAVLAIVAIVLAIEVALGWD   60
			  	61   QLAKAWVSLYRAKWWWLLAAVAAAGASMHSFAQIQRTLLKSAGVHVKQWRSEAAFYAANS  120
			  	121  LSTTLPGGPVLSATFLLRQQRIWGASTVVASWQLVMSGVLQAVGLALLGLGGAFFLGAKN  180
			  	181  NPFSLLFTLGGFVTLLLLAQAVASRPELIEGIGRRVLSWANSVRGRPADAGLPKWRETLM  240
			  	241  QLESVSLGRRDLGVAFGWSLFNWIADVACLGFAAYAAGDHASVGGLAVAYAAARAVGTIP  300
			  	301  LMPGGLLVVEAVLVPGLVSSGMPLPSAISAMLIYRLISWLLIAAIGWVVFFFMFRTESTA  360
			  	361  DSDNDRDPPTDPNLRLVIQPQGTPCDDPVETTPQGPAPTPDLRPEGGETPPR

Known structures in the PDB
No Known structures
1 42 83 124 165 206 247 288 329 370 411 Range: 35 to 347  |  Coverage: 75% UPF0104 Range: 48 to 332  |  Coverage: 68% 1 Range: to   |  Coverage: 0% 1
Number of amino acids : 412
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
UPF0104PF0370635-347
Mtb Structural Proteome models
Model Number1
Model nameRv0204c
Template1KPL    APDBCREDO
Template coverage48_379
Template Identity(%)16.5
Model coverage(%)68.9
Normalized DOPE score1.572

Structure Models from Chopin
Model Number1
Profileg.25.1.1 - 2.10.160.10
Click for model details
zscore4.26
Residue begin
Residue end
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0204cGene nameConfidence Score
Rv0205Rv02050.934
Rv0208cRv0208c0.92
Rv0206cmmpL30.918
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions