Rv0206c

Tuberculist information
Gene namemmpL3
Protein functionPossible conserved transmembrane transport protein MmpL3
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)244.484
Molecular mass(da)100872
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 944
	  		  	1    VFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQV   60
			  	61   YGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGM  120
			  	121  ATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGTVKLAGLQPVAEALTGTIATD  180
			  	181  QRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV  240
			  	241  VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLL  300
			  	301  LFPQGFLKSLTYATIASVMLSAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKIS  360
			  	361  AAYLNWLADRLQRTKTREEVEAGFWGKLVNRVMKRPVLFAAPIVIIMILLIIPVGKLSLG  420
			  	421  GISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTDAQIADIRSKAMAIG  480
			  	481  GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVL  540
			  	541  VGGTPALELDSIHGLFAKMPLMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMG  600
			  	601  ILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQ  660
			  	661  EAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP  720
			  	721  SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAG  780
			  	781  DPRPPHDPTHPLAESPRPARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPT  840
			  	841  TRLAAAGRSVQSPASTPPPTPTPPSAPSAGQTRAMPLAANRSTDAAGDPAEPTAALPIIR  900
			  	901  SDGDDSEAATEQLNARGTSDKTRQRRRGGGALSAQDLLRREGRL

Known structures in the PDB
No Known structures
1 95 189 283 377 471 565 659 753 847 941 Range: 43 to 399  |  Coverage: 37% MMPL Range: 425 to 745  |  Coverage: 33% MMPL Range: 1 to 733  |  Coverage: 77% 1
Number of amino acids : 944
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
MMPLPF0317643-399
MMPLPF03176425-745
Mtb Structural Proteome models
Model Number1
Model nameRv0206c
Template1T9X    APDBCREDO
Template coverage154_1036
Template Identity(%)14.3
Model coverage(%)77.5
Normalized DOPE score1.425

Structure Models from Chopin
CHOPIN models not available for this query
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0206cGene nameConfidence Score
Rv0204cRv0204c0.918
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions