Rv0127

Tuberculist information
Gene namemak
Protein functionMaltokinase Mak
Functional category(tuberculist)virulence,detoxification and adaptaion
Gene location(kb)154.232
Molecular mass(da)49879.1
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 455
	  		  	1    MTRSDTLATKLPWSDWLSRQRWYAGRNRELATVKPGVVVALRHNLDLVLVDVTYTDGATE   60
			  	61   RYQVLVGWDFEPASEYGTKAAIGVADDRTGFDALYDVAGPQFLLSLIVSSAVCGTSTGEV  120
			  	121  TFTREPDVELPFAAQPRVCDAEQSNTSVIFDRRAILKVFRRVSSGINPDIELNRVLTRAG  180
			  	181  NPHVARLLGAYQFGRPNRSPTDALAYALGMVTEYEANAAEGWAMATASVRDLFAEGDLYA  240
			  	241  HEVGGDFAGESYRLGEAVASVHATLADSLGTAQATFPVDRMLARLSSTVAVVPELREYAP  300
			  	301  TIEQQFQKLAAEAITVQRVHGDLHLGQVLRTPESWLLIDFEGEPGQPLDERRAPDSPLRD  360
			  	361  VAGVLRSFEYAAYGPLVDQATDKQLAARAREWVERNRAAFCDGYAVASGIDPRDSALLLG  420
			  	421  AYELDKAVYETGYETRHRPGWLPIPLRSIARLTAS

Known structures in the PDB
No Known structures
1 46 91 136 181 226 271 316 361 406 451 Range: 235 to 400  |  Coverage: 36% APH Range: 1 to 455  |  Coverage: 99% 1
Number of amino acids : 455
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
APHPF01636235-400
Mtb Structural Proteome models
Structure models not available for this query
Structure Models from Chopin
Model Number1
Profiled.144.1.6
Click for model details
zscore6.35
Residue begin1
Residue end455
Binding pockets
Structure models not available for this query
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0127Gene nameConfidence Score
Rv0126treS0.999
Rv0126treS0.999
Rv1326cglgB0.993
Rv1326cglgB0.993
Rv1326cglgB0.993
Rv1327cglgE0.991
Rv1327cglgE0.991
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions