SInCRe - Rv1484

Tuberculist information

Gene name	inhA
Protein function	NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase)
Functional category(tuberculist)	lipid metabolism
Gene location(kb)	1674.2
Molecular mass(da)	28527.8
External sites	TB Database TubercuList WebTB

Protein sequence

Number of amino acids : 269

	  		  	1    MTGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPL   60
			  	61   LELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGI  120
			  	121  HISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAG  180
			  	181  KYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAK  240
			  	241  TVCALLSDWLPATTGDIIYADGGAHTQLL

Known structures in the PDB

	PDB ID	1BVR
	Total residue count	1608
	Number of chains	6
	Method	X-RAY
	Resolution	2.8

	PDB ID	1ENY
	Total residue count	268
	Number of chains	1
	Method	X-RAY
	Resolution	2.2

	PDB ID	1ENZ
	Total residue count	268
	Number of chains	1
	Method	X-RAY
	Resolution	2.7

	PDB ID	1P44
	Total residue count	1614
	Number of chains	6
	Method	X-RAY
	Resolution	2.7

	PDB ID	1P45
	Total residue count	538
	Number of chains	2
	Method	X-RAY
	Resolution	2.6

	PDB ID	1ZID
	Total residue count	268
	Number of chains	1
	Method	X-RAY
	Resolution	2.7

	PDB ID	2AQ8
	Total residue count	269
	Number of chains	1
	Method	X-RAY
	Resolution	1.92

	PDB ID	2AQH
	Total residue count	269
	Number of chains	1
	Method	X-RAY
	Resolution	2.01

	PDB ID	2AQI
	Total residue count	269
	Number of chains	1
	Method	X-RAY
	Resolution	2.2

	PDB ID	2AQK
	Total residue count	269
	Number of chains	1
	Method	X-RAY
	Resolution	2.3

	PDB ID	2B35
	Total residue count	1614
	Number of chains	6
	Method	X-RAY
	Resolution	2.3

	PDB ID	2B36
	Total residue count	1614
	Number of chains	6
	Method	X-RAY
	Resolution	2.8

	PDB ID	2B37
	Total residue count	1614
	Number of chains	6
	Method	X-RAY
	Resolution	2.6

	PDB ID	2H9I
	Total residue count	268
	Number of chains	1
	Method	X-RAY
	Resolution	2.2

	PDB ID	2IDZ
	Total residue count	268
	Number of chains	1
	Method	X-RAY
	Resolution	2

	PDB ID	2IE0
	Total residue count	268
	Number of chains	1
	Method	X-RAY
	Resolution	2.2

	PDB ID	2IEB
	Total residue count	268
	Number of chains	1
	Method	X-RAY
	Resolution	2.2

	PDB ID	2IED
	Total residue count	1072
	Number of chains	4
	Method	X-RAY
	Resolution	2.14

	PDB ID	2NSD
	Total residue count	538
	Number of chains	2
	Method	X-RAY
	Resolution	1.9

	PDB ID	2NTJ
	Total residue count	536
	Number of chains	2
	Method	X-RAY
	Resolution	2.5

	PDB ID	2NV6
	Total residue count	268
	Number of chains	1
	Method	X-RAY
	Resolution	1.9

	PDB ID	2PR2
	Total residue count	269
	Number of chains	1
	Method	X-RAY
	Resolution	2.5

	PDB ID	2X22
	Total residue count	538
	Number of chains	2
	Method	X-RAY
	Resolution	2.1

	PDB ID	2X23
	Total residue count	1076
	Number of chains	4
	Method	X-RAY
	Resolution	1.81

	PDB ID	3FNE
	Total residue count	1076
	Number of chains	4
	Method	X-RAY
	Resolution	1.98

	PDB ID	3FNF
	Total residue count	1076
	Number of chains	4
	Method	X-RAY
	Resolution	2.3

	PDB ID	3FNG
	Total residue count	269
	Number of chains	1
	Method	X-RAY
	Resolution	1.97

	PDB ID	3FNH
	Total residue count	269
	Number of chains	1
	Method	X-RAY
	Resolution	2.8

	PDB ID	3OEW
	Total residue count	269
	Number of chains	1
	Method	X-RAY
	Resolution	2.2

	PDB ID	3OEY
	Total residue count	269
	Number of chains	1
	Method	X-RAY
	Resolution	2

	PDB ID	3OF2
	Total residue count	269
	Number of chains	1
	Method	X-RAY
	Resolution	2

	PDB ID	4BGE
	Total residue count	1614
	Number of chains	6
	Method	X-RAY
	Resolution	2.25

	PDB ID	4BGI
	Total residue count	1686
	Number of chains	6
	Method	X-RAY
	Resolution	2.09

	PDB ID	4BII
	Total residue count	1076
	Number of chains	4
	Method	X-RAY
	Resolution	1.95

	PDB ID	4BQP
	Total residue count	1614
	Number of chains	6
	Method	X-RAY
	Resolution	1.89

	PDB ID	4BQR
	Total residue count	1076
	Number of chains	4
	Method	X-RAY
	Resolution	2.05

	PDB ID	4COD
	Total residue count	1076
	Number of chains	4
	Method	X-RAY
	Resolution	2.4

	PDB ID	4DQU
	Total residue count	269
	Number of chains	1
	Method	X-RAY
	Resolution	2.45

	PDB ID	4DRE
	Total residue count	269
	Number of chains	1
	Method	X-RAY
	Resolution	2.4

	PDB ID	4DTI
	Total residue count	269
	Number of chains	1
	Method	X-RAY
	Resolution	1.9

	PDB ID	4OHU
	Total residue count	1156
	Number of chains	4
	Method	X-RAY
	Resolution	1.6

	PDB ID	4OIM
	Total residue count	289
	Number of chains	1
	Method	X-RAY
	Resolution	1.85

	PDB ID	4OXK
	Total residue count	1156
	Number of chains	4
	Method	X-RAY
	Resolution	1.84

	PDB ID	4OXN
	Total residue count	578
	Number of chains	2
	Method	X-RAY
	Resolution	2.29

	PDB ID	4OXY
	Total residue count	1156
	Number of chains	4
	Method	X-RAY
	Resolution	2.35

	PDB ID	4OYR
	Total residue count	1156
	Number of chains	4
	Method	X-RAY
	Resolution	2.3

	PDB ID	4TRJ
	Total residue count	269
	Number of chains	1
	Method	X-RAY
	Resolution	1.73

	PDB ID	4TZK
	Total residue count	269
	Number of chains	1
	Method	X-RAY
	Resolution	1.62

	PDB ID	4TZT
	Total residue count	269
	Number of chains	1
	Method	X-RAY
	Resolution	1.86

	PDB ID	4U0J
	Total residue count	269
	Number of chains	1
	Method	X-RAY
	Resolution	1.62

	PDB ID	4U0K
	Total residue count	269
	Number of chains	1
	Method	X-RAY
	Resolution	1.9

Number of amino acids : 269

Domains assigned based on sequence.

Mtb Structural proteome models

CHOPIN models

Profile-based domain assignment

Structural/Functional domain family	Pfam acc.no./SCOP ID	Domain Region
adh_short_C2	PF13561	14-265

Mtb Structural Proteome models

Model Number	1
Model name	Rv1484_2h7m_A
Template	2H7M APDB CREDO
Template coverage	2_269
Template Identity(%)	100.0
Model coverage(%)	99.3
Normalized DOPE score	-1.297

Model Number	2
Model name	Rv1484
Template	2AQ8 APDB CREDO
Template coverage	3_269
Template Identity(%)	100.0
Model coverage(%)	98.9
Normalized DOPE score	-1.181

Structure Models from Chopin

Model Number	1
Profile	c.2.1.2 - 3.40.50.720 Click for model details
zscore	25.66
Residue begin	1
Residue end	269

Binding pockets

STRING

Cytoscape Web will replace the contents of this div with protein-protein interaction network.

Protein interacting with Rv1484	Gene name	Confidence Score
Rv0533c	fabH	0.997
Rv0533c	fabH	0.997
Rv0533c	fabH	0.997
Rv2245	kasA	0.996
Rv2245	kasA	0.996
Rv2246	kasB	0.992
Rv2246	kasB	0.992
Rv2244	acpM	0.989
Rv1483	fabG1	0.938

Potential ligand/drug binding sites

Protein Model	Pocket Number	Drug Binding Site	PMIN Score	Pvalue PMIN	PMAX Score	Pvalue PMAX
Rv1484_2h7m_A	1	3ri5_IVM_B_349 PDB CREDO	0.607	0.171	0.607	0.002
Rv1484_2h7m_A	1	3rhw_IVM_B_349 PDB CREDO	0.606	0.172	0.606	0.002
Rv1484_2h7m_A	1	3rhw_IVM_D_348 PDB CREDO	0.603	0.175	0.603	0.002
Rv1484_2h7m_A	1	3rhw_IVM_B_348 PDB CREDO	0.602	0.177	0.602	0.002
Rv1484_2h7m_A	1	3ri5_IVM_D_349 PDB CREDO	0.602	0.177	0.602	0.002
Rv1484_2h7m_A	1	3ria_IVM_A_348 PDB CREDO	0.602	0.177	0.602	0.002
Rv1484_2h7m_A	1	3rif_IVM_E_402 PDB CREDO	0.601	0.178	0.601	0.002
Rv1484_2h7m_A	1	3ria_IVM_C_350 PDB CREDO	0.600	0.179	0.600	0.002
Rv1484_2h7m_A	1	3rhw_IVM_D_349 PDB CREDO	0.599	0.180	0.599	0.002
Rv1484_2h7m_A	1	3ria_IVM_E_348 PDB CREDO	0.598	0.181	0.598	0.002
Rv1484_2h7m_A	1	3rhw_IVM_A_348 PDB CREDO	0.592	0.188	0.592	0.002
Rv1484_2h7m_A	1	3ri5_IVM_A_349 PDB CREDO	0.592	0.188	0.592	0.002
Rv1484_2h7m_A	1	3ria_IVM_E_349 PDB CREDO	0.587	0.195	0.587	0.003
Rv1484_2h7m_A	1	3ri5_IVM_E_349 PDB CREDO	0.625	0.150	0.578	0.003
Rv1484_2h7m_A	3	3jwq_VIA_D_901 PDB CREDO	0.635	0.139	0.575	0.003
Rv1484_2h7m_A	1	3sxr_1N1_A_1 PDB CREDO	0.618	0.158	0.572	0.003
Rv1484_2h7m_A	3	3gws_T3_X_500 PDB CREDO	0.568	0.219	0.568	0.004
Rv1484_2h7m_A	1	3bbt_FMM_B_91 PDB CREDO	0.567	0.221	0.567	0.004
Rv1484_2h7m_A	1	1ya3_STR_C_3001 PDB CREDO	0.610	0.167	0.566	0.004
Rv1484_2h7m_A	3	3ln1_CEL_C_682 PDB CREDO	0.562	0.227	0.562	0.004
Rv1484_2h7m_A	3	3ln1_CEL_A_682 PDB CREDO	0.562	0.228	0.562	0.004
Rv1484_2h7m_A	3	3ln1_CEL_B_682 PDB CREDO	0.561	0.229	0.561	0.004
Rv1484_2h7m_A	3	1lhv_NOG_A_301 PDB CREDO	0.578	0.206	0.560	0.004
Rv1484_2h7m_A	3	1bsx_T3_A_1 PDB CREDO	0.559	0.231	0.559	0.004
Rv1484_2h7m_A	3	1bsx_T3_B_2 PDB CREDO	0.559	0.231	0.559	0.004
Rv1484_2h7m_A	1	3rif_IVM_A_402 PDB CREDO	0.623	0.152	0.558	0.004
Rv1484_2h7m_A	1	3rif_IVM_B_403 PDB CREDO	0.623	0.152	0.558	0.004
Rv1484_2h7m_A	3	2hw2_RFP_A_1200 PDB CREDO	0.594	0.186	0.558	0.004
Rv1484_2h7m_A	1	3ri5_IVM_C_350 PDB CREDO	0.623	0.153	0.557	0.004
Rv1484_2h7m_A	1	3rif_IVM_D_402 PDB CREDO	0.623	0.153	0.557	0.004
Rv1484_2h7m_A	1	3ria_IVM_C_349 PDB CREDO	0.621	0.155	0.556	0.005
Rv1484_2h7m_A	1	1lhu_EST_A_301 PDB CREDO	0.643	0.131	0.555	0.005
Rv1484_2h7m_A	1	3sxr_1N1_B_2 PDB CREDO	0.622	0.154	0.553	0.005
Rv1484_2h7m_A	3	2h79_T3_A_1 PDB CREDO	0.568	0.219	0.550	0.005
Rv1484_2h7m_A	1	1ya3_STR_B_2001 PDB CREDO	0.659	0.116	0.549	0.005
Rv1484_2h7m_A	3	3uvv_T3_A_501 PDB CREDO	0.566	0.222	0.548	0.005
Rv1484_2h7m_A	1	2ito_IRE_A_2020 PDB CREDO	0.548	0.247	0.548	0.005
Rv1484_2h7m_A	1	3ls4_TCI_H_220 PDB CREDO	0.592	0.188	0.548	0.005
Rv1484_2h7m_A	3	1fm6_BRL_X_504 PDB CREDO	0.566	0.222	0.548	0.005
Rv1484_2h7m_A	1	3aod_RFP_C_2002 PDB CREDO	0.590	0.191	0.547	0.005
Rv1484_2h7m_A	1	1a27_EST_A_350 PDB CREDO	0.569	0.219	0.547	0.005
Rv1484_2h7m_A	3	1xzx_T3_X_500 PDB CREDO	0.565	0.224	0.547	0.005
Rv1484_2h7m_A	1	3h52_486_C_4 PDB CREDO	0.610	0.167	0.546	0.005
Rv1484_2h7m_A	3	2x9g_LYA_A_1270 PDB CREDO	0.564	0.225	0.546	0.005
Rv1484_2h7m_A	3	2h77_T3_A_1 PDB CREDO	0.582	0.201	0.545	0.005
Rv1484_2h7m_A	1	3adx_IMN_B_3 PDB CREDO	0.613	0.164	0.545	0.005
Rv1484_2h7m_A	1	3rif_IVM_A_403 PDB CREDO	0.609	0.169	0.545	0.005
Rv1484_2h7m_A	3	1z2b_VLB_C_800 PDB CREDO	0.637	0.138	0.545	0.005
Rv1484_2h7m_A	3	3ln1_CEL_D_682 PDB CREDO	0.599	0.180	0.542	0.006
Rv1484_2h7m_A	3	3ua1_08Y_A_600 PDB CREDO	0.559	0.232	0.541	0.006
Rv1484_2h7m_A	1	2h42_VIA_B_902 PDB CREDO	0.604	0.174	0.541	0.006
Rv1484_2h7m_A	3	1uwh_BAX_B_1723 PDB CREDO	0.611	0.166	0.539	0.006
Rv1484_2h7m_A	3	1qkn_RAL_A_600 PDB CREDO	0.539	0.260	0.539	0.006
Rv1484_2h7m_A	3	3nrr_D16_B_520 PDB CREDO	0.616	0.160	0.539	0.006
Rv1484_2h7m_A	3	1uwh_BAX_A_1723 PDB CREDO	0.611	0.166	0.538	0.006
Rv1484_2h7m_A	1	1ya3_STR_A_1001 PDB CREDO	0.644	0.130	0.537	0.006
Rv1484_2h7m_A	3	2h42_VIA_A_901 PDB CREDO	0.593	0.187	0.537	0.006
Rv1484_2h7m_A	1	1jin_KTN_A_801 PDB CREDO	0.579	0.205	0.536	0.006
Rv1484_2h7m_A	1	2h42_VIA_C_903 PDB CREDO	0.598	0.181	0.535	0.006
Rv1484_2h7m_A	3	3jwq_VIA_B_901 PDB CREDO	0.656	0.118	0.535	0.006
Rv1484_2h7m_A	1	3k54_1N1_A_1 PDB CREDO	0.575	0.210	0.534	0.006
Rv1484_2h7m_A	1	3jwq_VIA_B_901 PDB CREDO	0.596	0.184	0.533	0.007
Rv1484_2h7m_A	1	1p93_DEX_B_2999 PDB CREDO	0.662	0.113	0.533	0.007
Rv1484_2h7m_A	3	1uwj_BAX_B_1723 PDB CREDO	0.642	0.132	0.533	0.007
Rv1484_2h7m_A	1	3kw2_ADN_B_300 PDB CREDO	0.575	0.210	0.532	0.007
Rv1484_2h7m_A	3	3tne_RIT_A_401 PDB CREDO	0.566	0.222	0.531	0.007
Rv1484_2h7m_A	1	2w8y_NDR_B_1000 PDB CREDO	0.573	0.213	0.530	0.007
Rv1484_2h7m_A	1	2q1v_PDN_A_248 PDB CREDO	0.634	0.140	0.529	0.007
Rv1484_2h7m_A	3	3oct_1N1_A_663 PDB CREDO	0.604	0.175	0.528	0.007
Rv1484_2h7m_A	3	1uwj_BAX_A_1723 PDB CREDO	0.693	0.086	0.527	0.007
Rv1484_2h7m_A	3	1uob_PNN_A_1311 PDB CREDO	0.616	0.160	0.527	0.007
Rv1484_2h7m_A	1	1jip_KTN_A_801 PDB CREDO	0.617	0.159	0.527	0.007
Rv1484_2h7m_A	3	1zgy_BRL_A_503 PDB CREDO	0.562	0.227	0.526	0.007
Rv1484_2h7m_A	1	2ity_IRE_A_2020 PDB CREDO	0.569	0.219	0.526	0.007
Rv1484_2h7m_A	1	2aa5_STR_A_301 PDB CREDO	0.698	0.082	0.526	0.007
Rv1484_2h7m_A	1	1jg3_ADN_A_500 PDB CREDO	0.566	0.222	0.525	0.007
Rv1484_2h7m_A	3	4eb6_VLB_C_503 PDB CREDO	0.645	0.130	0.525	0.007
Rv1484_2h7m_A	1	2cbr_A80_A_201 PDB CREDO	0.545	0.251	0.525	0.007
Rv1484_2h7m_A	1	2itz_IRE_A_2021 PDB CREDO	0.590	0.191	0.525	0.007
Rv1484_2h7m_A	1	2aa5_STR_B_302 PDB CREDO	0.696	0.084	0.524	0.008
Rv1484_2h7m_A	1	1p93_DEX_A_1999 PDB CREDO	0.650	0.124	0.524	0.008
Rv1484_2h7m_A	3	3qt0_486_A_4 PDB CREDO	0.578	0.206	0.523	0.008
Rv1484_2h7m_A	3	2x9g_LYA_B_1270 PDB CREDO	0.557	0.234	0.521	0.008
Rv1484_2h7m_A	1	1mx1_THA_D_4 PDB CREDO	0.563	0.226	0.521	0.008
Rv1484_2h7m_A	1	3bbt_FMM_D_91 PDB CREDO	0.647	0.128	0.521	0.008
Rv1484_2h7m_A	1	1a28_STR_A_1 PDB CREDO	0.603	0.175	0.521	0.008
Rv1484_2h7m_A	3	3d91_REM_A_350 PDB CREDO	0.627	0.149	0.520	0.008
Rv1484_2h7m_A	3	2gqg_1N1_B_502 PDB CREDO	0.537	0.262	0.520	0.008
Rv1484_2h7m_A	3	1cil_ETS_A_263 PDB CREDO	0.573	0.212	0.519	0.008
Rv1484_2h7m_A	3	2h42_VIA_B_902 PDB CREDO	0.634	0.140	0.517	0.008
Rv1484_2h7m_A	1	2aa6_STR_A_401 PDB CREDO	0.686	0.092	0.516	0.009
Rv1484_2h7m_A	1	1jg3_ADN_B_550 PDB CREDO	0.536	0.264	0.516	0.009
Rv1484_2h7m_A	3	3d91_REM_B_350 PDB CREDO	0.621	0.154	0.516	0.009
Rv1484_2h7m_A	1	2aax_PDN_B_503 PDB CREDO	0.684	0.093	0.515	0.009
Rv1484_2h7m_A	1	1ict_T44_C_128 PDB CREDO	0.604	0.175	0.515	0.009
Rv1484_2h7m_A	1	2aa6_STR_B_402 PDB CREDO	0.683	0.095	0.514	0.009
Rv1484_2h7m_A	3	3frq_ERY_B_195 PDB CREDO	0.548	0.247	0.514	0.009
Rv1484_2h7m_A	1	2uxo_TAC_B_1211 PDB CREDO	0.578	0.206	0.514	0.009
Rv1484_2h7m_A	1	2aax_PDN_A_502 PDB CREDO	0.682	0.095	0.514	0.009
Rv1484_2h7m_A	1	2w9s_TOP_D_1158 PDB CREDO	0.627	0.148	0.513	0.009
Rv1484_2h7m_A	1	3f4x_KLT_A_300 PDB CREDO	0.513	0.298	0.513	0.009
Rv1484_2h7m_A	3	1kij_NOV_A_400 PDB CREDO	0.566	0.222	0.512	0.009
Rv1484_2h7m_A	3	3k2h_LYA_B_514 PDB CREDO	0.607	0.171	0.512	0.009
Rv1484_2h7m_A	1	1mx1_THA_C_3 PDB CREDO	0.593	0.188	0.512	0.009
Rv1484_2h7m_A	3	1y0x_T44_X_500 PDB CREDO	0.581	0.203	0.512	0.009
Rv1484_2h7m_A	1	1mx1_THA_F_6 PDB CREDO	0.553	0.240	0.512	0.009
Rv1484_2h7m_A	1	3jwq_VIA_D_901 PDB CREDO	0.635	0.140	0.511	0.009
Rv1484_2h7m_A	3	2x9g_LYA_D_1270 PDB CREDO	0.584	0.198	0.511	0.009
Rv1484_2h7m_A	3	3h0a_9RA_A_500 PDB CREDO	0.565	0.224	0.511	0.009
Rv1484_2h7m_A	1	2xkw_P1B_B_1475 PDB CREDO	0.570	0.216	0.510	0.009
Rv1484_2h7m_A	1	2h42_VIA_A_901 PDB CREDO	0.634	0.141	0.510	0.009
Rv1484_2h7m_A	3	3b0w_DGX_A_1 PDB CREDO	0.614	0.162	0.510	0.009
Rv1484_2h7m_A	1	1nhz_486_A_800 PDB CREDO	0.655	0.120	0.510	0.009
Rv1484_2h7m_A	1	1fdu_EST_C_353 PDB CREDO	0.529	0.274	0.509	0.009
Rv1484_2h7m_A	1	2ayl_FLP_A_1701 PDB CREDO	0.529	0.274	0.509	0.009
Rv1484_2h7m_A	1	3kw2_ADN_A_300 PDB CREDO	0.529	0.274	0.509	0.009
Rv1484_2h7m_A	3	3vn2_TLS_A_501 PDB CREDO	0.560	0.230	0.509	0.009
Rv1484_2h7m_A	3	2y6o_1N1_A_1892 PDB CREDO	0.526	0.279	0.509	0.009
Rv1484_2h7m_A	3	2x9g_LYA_C_1270 PDB CREDO	0.582	0.201	0.509	0.010
Rv1484_2h7m_A	1	1mx1_THA_E_5 PDB CREDO	0.548	0.247	0.508	0.010
Rv1484_2h7m_A	3	4eyb_0WO_A_303 PDB CREDO	0.602	0.176	0.508	0.010
Rv1484_2h7m_A	3	3tne_RIT_B_401 PDB CREDO	0.542	0.256	0.508	0.010
Rv1484_2h7m_A	1	3oht_1N1_A_1000 PDB CREDO	0.527	0.277	0.507	0.010
Rv1484_2h7m_A	1	1ie4_T44_B_328 PDB CREDO	0.527	0.277	0.507	0.010
Rv1484_2h7m_A	1	1m17_AQ4_A_999 PDB CREDO	0.594	0.186	0.507	0.010
Rv1484_2h7m_A	1	2ayl_FLP_B_2701 PDB CREDO	0.594	0.187	0.507	0.010
Rv1484_2h7m_A	1	1lhv_NOG_A_301 PDB CREDO	0.718	0.068	0.506	0.010
Rv1484_2h7m_A	1	1sqn_NDR_B_2001 PDB CREDO	0.586	0.197	0.506	0.010
Rv1484_2h7m_A	3	3oez_STI_B_601 PDB CREDO	0.538	0.261	0.505	0.010
Rv1484_2h7m_A	3	3ads_IMN_A_2 PDB CREDO	0.577	0.207	0.504	0.010
Rv1484_2h7m_A	3	3aod_RFP_C_2002 PDB CREDO	0.642	0.132	0.504	0.010
Rv1484_2h7m_A	1	1sqn_NDR_A_1001 PDB CREDO	0.584	0.198	0.504	0.010
Rv1484_2h7m_A	1	2xpv_MIY_A_1209 PDB CREDO	0.583	0.200	0.503	0.010
Rv1484_2h7m_A	3	3apw_DP0_A_190 PDB CREDO	0.520	0.288	0.503	0.010
Rv1484_2h7m_A	3	3o1c_ADN_A_127 PDB CREDO	0.640	0.134	0.503	0.010
Rv1484_2h7m_A	3	2fum_MIX_D_3539 PDB CREDO	0.555	0.237	0.502	0.011
Rv1484_2h7m_A	3	1nhz_486_A_800 PDB CREDO	0.536	0.264	0.502	0.011
Rv1484_2h7m_A	3	2cbr_A80_A_201 PDB CREDO	0.663	0.112	0.502	0.011

Similarity to known drug target from sensitive sequence analysis

No drug targets

List of small molecules tested from TIBLE

View results in TIBLE page

Name	Affinity	Assay description	DOI
CHEMBL1253716	Inhibition = 87 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli at 1 uM after 2 hrs	http://www.ncbi.nlm.nih.gov/pubmed/20696503
CHEMBL1253716	Inhibition = 67 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli at 1 uM after 5 mins	http://www.ncbi.nlm.nih.gov/pubmed/20696503
CHEMBL1253716	Inhibition = 97 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli at 10 uM after 2 hrs	http://www.ncbi.nlm.nih.gov/pubmed/20696503
CHEMBL1253716	Inhibition = 92 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli at 10 uM after 5 mins	http://www.ncbi.nlm.nih.gov/pubmed/20696503
CHEMBL1253731	Inhibition = 20 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli at 100 uM after 5 mins	http://www.ncbi.nlm.nih.gov/pubmed/20696503
CHEMBL1253732	Inhibition = 17 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli at 100 uM after 5 mins	http://www.ncbi.nlm.nih.gov/pubmed/20696503
CHEMBL1254640	Inhibition = 23 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli at 100 uM after 5 mins	http://www.ncbi.nlm.nih.gov/pubmed/20696503
CHEMBL1254641	Inhibition = 12 %	Inhibition of Mycobacterium tuberculosis InhA using 2-trans-decenoyl-CoA as substrate at 30 uM after 5 mins by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21975068
CHEMBL1254641	Inhibition = 41 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli at 100 uM after 5 mins	http://www.ncbi.nlm.nih.gov/pubmed/20696503
CHEMBL1254641	Inhibition = 80 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli at 100 uM after 2 hrs	http://www.ncbi.nlm.nih.gov/pubmed/20696503
CHEMBL1254641	Inhibition = 27 %	Inhibition of Mycobacterium tuberculosis InhA using 2-trans-decenoyl-CoA as substrate at 100 uM after 5 mins by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21975068
CHEMBL1254721	Inhibition = 4 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli at 100 uM after 5 mins	http://www.ncbi.nlm.nih.gov/pubmed/20696503
CHEMBL1254721	Inhibition = 4 %	Inhibition of Mycobacterium tuberculosis InhA using 2-trans-decenoyl-CoA as substrate at 100 uM after 5 mins by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21975068
CHEMBL1254722	Inhibition = 9 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli at 100 uM after 5 mins	http://www.ncbi.nlm.nih.gov/pubmed/20696503
CHEMBL1254804	Inhibition = 17 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli at 100 uM after 5 mins	http://www.ncbi.nlm.nih.gov/pubmed/20696503
CHEMBL1254805	Inhibition = 40 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli at 20 uM after 5 mins	http://www.ncbi.nlm.nih.gov/pubmed/20696503
CHEMBL1254805	Inhibition = 28 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli at 20 uM after 2 hrs	http://www.ncbi.nlm.nih.gov/pubmed/20696503
CHEMBL1254805	Inhibition = 91 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli at 100 uM after 5 mins	http://www.ncbi.nlm.nih.gov/pubmed/20696503
CHEMBL1254805	Inhibition = 19 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli at 10 uM after 5 mins	http://www.ncbi.nlm.nih.gov/pubmed/20696503
CHEMBL1254890	Inhibition = 25 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli at 10 uM after 5 mins	http://www.ncbi.nlm.nih.gov/pubmed/20696503
CHEMBL1254891	Inhibition = 35 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli at 100 uM after 5 mins	http://www.ncbi.nlm.nih.gov/pubmed/20696503
CHEMBL1254977	Inhibition = 30 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli at 100 uM after 5 mins	http://www.ncbi.nlm.nih.gov/pubmed/20696503
CHEMBL1254978	Inhibition = 6 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli at 100 uM after 5 mins	http://www.ncbi.nlm.nih.gov/pubmed/20696503
CHEMBL1255062	Inhibition = 3 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli at 100 uM after 5 mins	http://www.ncbi.nlm.nih.gov/pubmed/20696503
CHEMBL1269411	Ki = 2.1 uM	Inhibition of Mycobacterium tuberculosis inhA	http://www.ncbi.nlm.nih.gov/pubmed/20855214
CHEMBL1825039	Inhibition = 21 %	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate at 50 uM	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL1825041	Inhibition = 44 %	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate at 50 uM	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL1825043	Not Active	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21 using trans-2-dodecenoyl-Coenzyme A as substrate at 10 uM by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21944473
CHEMBL1833987	Inhibition = 23 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21 using trans-2-dodecenoyl-Coenzyme A as substrate at 10 uM by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21944473
CHEMBL1833987	Inhibition = 46 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21 using trans-2-dodecenoyl-Coenzyme A as substrate at 50 uM by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21944473
CHEMBL1835154	Inhibition = 13 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21 using trans-2-dodecenoyl-Coenzyme A as substrate at 50 uM by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21944473
CHEMBL1835155	Inhibition = 10 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21 using trans-2-dodecenoyl-Coenzyme A as substrate at 50 uM by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21944473
CHEMBL1835156	Not Active	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21 using trans-2-dodecenoyl-Coenzyme A as substrate at 10 uM by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21944473
CHEMBL1835157	Inhibition = 10 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21 using trans-2-dodecenoyl-Coenzyme A as substrate at 50 uM by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21944473
CHEMBL1835158	Not Active	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21 using trans-2-dodecenoyl-Coenzyme A as substrate at 10 uM by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21944473
CHEMBL1835159	Inhibition = 14 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21 using trans-2-dodecenoyl-Coenzyme A as substrate at 10 uM by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21944473
CHEMBL1835159	Inhibition = 25 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21 using trans-2-dodecenoyl-Coenzyme A as substrate at 50 uM by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21944473
CHEMBL1835160	Inhibition = 12 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21 using trans-2-dodecenoyl-Coenzyme A as substrate at 50 uM by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21944473
CHEMBL1835161	Not Active	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21 using trans-2-dodecenoyl-Coenzyme A as substrate at 10 uM by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21944473
CHEMBL1835235	Not Active	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21 using trans-2-dodecenoyl-Coenzyme A as substrate at 10 uM by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21944473
CHEMBL1835236	Not Active	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21 using trans-2-dodecenoyl-Coenzyme A as substrate at 10 uM by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21944473
CHEMBL1835237	Not Active	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21 using trans-2-dodecenoyl-Coenzyme A as substrate at 10 uM by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21944473
CHEMBL1835238	Not Active	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21 using trans-2-dodecenoyl-Coenzyme A as substrate at 10 uM by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21944473
CHEMBL1835239	Not Active	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21 using trans-2-dodecenoyl-Coenzyme A as substrate at 10 uM by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21944473
CHEMBL1835240	Not Active	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21 using trans-2-dodecenoyl-Coenzyme A as substrate at 10 uM by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21944473
CHEMBL1835241	Not Active	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21 using trans-2-dodecenoyl-Coenzyme A as substrate at 10 uM by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21944473
CHEMBL1835243	Not Active	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21 using trans-2-dodecenoyl-Coenzyme A as substrate at 10 uM by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21944473
CHEMBL1835244	Not Active	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21 using trans-2-dodecenoyl-Coenzyme A as substrate at 10 uM by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21944473
CHEMBL1835244	Inhibition = 15 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21 using trans-2-dodecenoyl-Coenzyme A as substrate at 50 uM by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21944473
CHEMBL1835245	Inhibition = 11 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21 using trans-2-dodecenoyl-Coenzyme A as substrate at 50 uM by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21944473
CHEMBL1835246	Not Active	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21 using trans-2-dodecenoyl-Coenzyme A as substrate at 10 uM by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21944473
CHEMBL1835247	Not Active	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21 using trans-2-dodecenoyl-Coenzyme A as substrate at 10 uM by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21944473
CHEMBL1835248	Inhibition = 58 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21 using trans-2-dodecenoyl-Coenzyme A as substrate at 50 uM by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21944473
CHEMBL1835249	Inhibition = 40 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21 using trans-2-dodecenoyl-Coenzyme A as substrate at 50 uM by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21944473
CHEMBL1914612	Inhibition = 28 %	Inhibition of Mycobacterium tuberculosis InhA using 2-trans-decenoyl-CoA as substrate at 30 uM after 5 mins by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21975068
CHEMBL1914612	Inhibition = 67 %	Inhibition of Mycobacterium tuberculosis InhA using 2-trans-decenoyl-CoA as substrate at 100 uM after 5 mins by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21975068
CHEMBL1914613	Inhibition = 12 %	Inhibition of Mycobacterium tuberculosis InhA using 2-trans-decenoyl-CoA as substrate at 100 uM after 5 mins by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21975068
CHEMBL1914614	Inhibition = 16 %	Inhibition of Mycobacterium tuberculosis InhA using 2-trans-decenoyl-CoA as substrate at 100 uM after 5 mins by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21975068
CHEMBL1914614	Inhibition = 1 %	Inhibition of Mycobacterium tuberculosis InhA using 2-trans-decenoyl-CoA as substrate at 30 uM after 5 mins by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21975068
CHEMBL1914615	Inhibition = 0 %	Inhibition of Mycobacterium tuberculosis InhA using 2-trans-decenoyl-CoA as substrate at 100 uM after 5 mins by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21975068
CHEMBL1914615	Inhibition = 0 %	Inhibition of Mycobacterium tuberculosis InhA using 2-trans-decenoyl-CoA as substrate at 30 uM after 5 mins by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21975068
CHEMBL1914616	Inhibition = 0 %	Inhibition of Mycobacterium tuberculosis InhA using 2-trans-decenoyl-CoA as substrate at 100 uM after 5 mins by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21975068
CHEMBL1914617	Inhibition = 15 %	Inhibition of Mycobacterium tuberculosis InhA using 2-trans-decenoyl-CoA as substrate at 30 uM after 5 mins by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21975068
CHEMBL1914617	Inhibition = 66 %	Inhibition of Mycobacterium tuberculosis InhA using 2-trans-decenoyl-CoA as substrate at 100 uM after 5 mins by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21975068
CHEMBL1914618	Inhibition = 26 %	Inhibition of Mycobacterium tuberculosis InhA using 2-trans-decenoyl-CoA as substrate at 30 uM after 5 mins by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21975068
CHEMBL1914619	Inhibition = 1 %	Inhibition of Mycobacterium tuberculosis InhA using 2-trans-decenoyl-CoA as substrate at 30 uM after 5 mins by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21975068
CHEMBL1914619	Inhibition = 9 %	Inhibition of Mycobacterium tuberculosis InhA using 2-trans-decenoyl-CoA as substrate at 100 uM after 5 mins by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21975068
CHEMBL1914620	Inhibition = 13 %	Inhibition of Mycobacterium tuberculosis InhA using 2-trans-decenoyl-CoA as substrate at 100 uM after 5 mins by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21975068
CHEMBL1914620	Inhibition = 0 %	Inhibition of Mycobacterium tuberculosis InhA using 2-trans-decenoyl-CoA as substrate at 30 uM after 5 mins by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21975068
CHEMBL1914621	Inhibition = 10 %	Inhibition of Mycobacterium tuberculosis InhA using 2-trans-decenoyl-CoA as substrate at 100 uM after 5 mins by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21975068
CHEMBL1914622	Inhibition = 20 %	Inhibition of Mycobacterium tuberculosis InhA using 2-trans-decenoyl-CoA as substrate at 30 uM after 5 mins by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21975068
CHEMBL2023768	Inhibition = 54 %	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate at 50 uM	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL2023769	Inhibition < 5 %	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate at 50 uM	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL2023770	Inhibition = 35 %	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate at 50 uM	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL2023771	Inhibition = 10 %	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate at 50 uM	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL2023772	Inhibition = 43 %	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate at 50 uM	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL2023773	Inhibition = 67 %	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate at 50 uM	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL2023774	Inhibition = 21 %	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate at 50 uM	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL2023775	Not Active	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate at 50 uM	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL2023776	Inhibition = 48 %	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate at 50 uM	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL2023777	Inhibition = 61 %	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate at 50 uM	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL2023778	Inhibition = 37 %	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate at 50 uM	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL2023779	Inhibition = 58 %	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate at 50 uM	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL2023780	Inhibition = 73 %	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate at 50 uM	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL2023781	Inhibition = 75 %	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate at 50 uM	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL2023782	Inhibition = 58 %	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate at 50 uM	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL2023783	Inhibition = 34 %	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate at 50 uM	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL2023784	Inhibition = 52 %	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate at 50 uM	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL2023785	Not Active	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate at 50 uM	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL2023786	Inhibition = 20 %	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate at 50 uM	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL2023787	Inhibition = 46 %	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate at 50 uM	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL2023788	Inhibition = 24 %	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate at 50 uM	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL2023789	Inhibition = 19 %	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate at 50 uM	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL2023790	Not Active	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate at 50 uM	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL2023791	Inhibition = 42 %	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate at 50 uM	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL2023792	Not Active	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate at 50 uM	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL2023793	Inhibition = 33 %	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate at 50 uM	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL2023794	Inhibition = 9 %	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate at 50 uM	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL2023795	Inhibition = 33 %	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate at 50 uM	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL213720	IC50 > 100 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL213872	Inhibition = 78 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL213872	IC50 = 2.57 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL214484	IC50 = 16.79 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL214964	Not Active	Inhibition of Mycobacterium tuberculosis InhA at 20 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL215014	IC50 > 100 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL215081	IC50 = 56.5 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL215478	Inhibition = 72 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL215478	IC50 = 6.41 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL216063	IC50 > 100 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL216132	Not Active	Inhibition of Mycobacterium tuberculosis InhA at 20 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL216261	Not Active	Inhibition of Mycobacterium tuberculosis InhA at 20 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL216282	Inhibition = 3 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL216299	IC50 > 100 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL216339	IC50 = 3.67 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL216512	Inhibition = 83 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL216512	IC50 = 4.47 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL216547	IC50 > 100 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL216579	Inhibition = 94 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL216579	Inhibition = 97 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL216579	IC50 = 0.2 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL216642	IC50 = 3.94 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL216679	Inhibition = 66 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL216689	Inhibition > 90 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL216689	Inhibition = 72.7 %	Inhibition of Mycobacterium tuberculosis InhA at 2.4 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL216689	Inhibition = 90 %	Inhibition of Mycobacterium tuberculosis InhA at 1.5 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL216689	Inhibition = 70 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL216689	IC50 = 0.14 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL216704	IC50 = 1.3 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL216748	IC50 = 37.41 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL216759	IC50 = 29.23 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL216781	IC50 > 75 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL216786	IC50 = 10.59 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL216807	IC50 = 200 nM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL216807	IC50 = 8160 nM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL216807	IC50 = 0.39 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL216851	Inhibition = 70 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL216887	IC50 = 10.05 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217057	IC50 = 0.27 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217057	Inhibition > 90 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217057	Inhibition = 80 %	Inhibition of Mycobacterium tuberculosis InhA at 1.5 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217063	Not Active	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217069	Inhibition = 26 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217070	Inhibition = 32 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217144	IC50 = 56.02 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217187	Inhibition = 38 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217199	Not Active	Inhibition of Mycobacterium tuberculosis InhA at 20 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217204	IC50 = 13.55 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217211	Inhibition = 90 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217211	Inhibition = 25 %	Inhibition of Mycobacterium tuberculosis InhA at 1.5 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217258	Inhibition = 34 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217272	IC50 = 73.58 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217273	IC50 > 100 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217274	IC50 > 100 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217332	Not Active	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217375	IC50 > 100 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217499	IC50 = 5.1 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217499	Inhibition = 65 %	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217524	IC50 = 14.83 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217588	IC50 = 1.35 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217594	IC50 = 0.75 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217594	Inhibition = 64 %	Inhibition of Mycobacterium tuberculosis InhA at 1.5 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217594	Inhibition = 96 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217616	Inhibition = 51 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217617	IC50 = 31.37 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217619	Inhibition = 65 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217739	Not Active	Inhibition of Mycobacterium tuberculosis InhA at 20 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217773	IC50 > 100 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217808	IC50 > 100 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217852	Inhibition = 75 %	Inhibition of Mycobacterium tuberculosis InhA at 1.5 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217852	Inhibition > 90 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217852	IC50 = 0.46 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217864	IC50 = 34.88 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217879	IC50 = 5.18 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217879	Inhibition = 77 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217885	IC50 > 100 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL217926	IC50 = 10.66 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL239457	IC50 = 16.64 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL239459	IC50 = 9.43 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL239673	IC50 = 0.99 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL239674	IC50 = 9.74 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL239890	IC50 = 1.85 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL239891	IC50 > 100 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL239892	IC50 > 100 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL240105	IC50 = 6.73 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL240316	IC50 = 17.62 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL240317	IC50 = 31.5 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL240318	IC50 = 7.74 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL240530	IC50 = 5.16 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL240531	IC50 = 7.39 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL240533	IC50 = 0.09 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL240533	Inhibition = 97 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL240734	IC50 = 38.86 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL240739	Inhibition = 84 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL240739	IC50 = 1.04 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL240740	IC50 = 1.89 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL240740	Inhibition = 83 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL240957	Inhibition = 81 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL240957	IC50 = 2.04 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL240960	Inhibition = 81 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL241170	Inhibition = 81 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL241171	Inhibition = 77 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL241172	Inhibition = 74 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL250087	IC50 = 27 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17560106
CHEMBL258931	Ki = 1 nM	Inhibition of Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL258931	IC50 = 8200 nM	Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL258932	IC50 = 650 nM	Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL258932	Ki = 1 nM	Inhibition of Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL258933	Not Active	Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL258933	Ki = 1 nM	Inhibition of Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL259138	Ki = 1 nM	Inhibition of Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL259138	IC50 = 160 nM	Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL260399	Ki = 1 nM	Inhibition of Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL260399	IC50 = 130 nM	Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL261355	IC50 = 306 nM	Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL261355	Ki = 1 nM	Inhibition of Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL262343	Ki = 1 nM	Inhibition of Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL262343	IC50 = 1930 nM	Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL262360	IC50 = 1300 nM	Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL262360	Ki = 1 nM	Inhibition of Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL262471	IC50 = 5.51 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL262471	Inhibition = 50 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL263248	Inhibition = 56 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL263646	Ki = 1 nM	Inhibition of Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL263646	IC50 = 580 nM	Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL264175	IC50 = 55 nM	Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL264175	Ki = 1 nM	Inhibition of Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL264175	Ki = 40 nM	Inhibition of Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL264176	IC50 = 1550 nM	Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL264176	Ki = 1 nM	Inhibition of Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL264415	IC50 = 180 nM	Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL264415	Ki = 1 nM	Inhibition of Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL264416	Ki = 21 nM	Inhibition of Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL264416	IC50 = 48 nM	Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL264416	Ki = 1 nM	Inhibition of Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL264417	Ki = 1 nM	Inhibition of Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL264417	IC50 = 90 nM	Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL264434	Ki = 1 nM	Inhibition of Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL264434	Ki = 16 nM	Inhibition of Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL264434	IC50 = 62 nM	Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL264679	Ki = 1 nM	Inhibition of Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL264679	IC50 = 11500 nM	Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL264682	IC50 = 11 nM	Inhibition of 1 nM Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL264682	Ki = 1 nM	Inhibition of Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL265016	IC50 > 100 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL274325	IC50 > 100 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL276420	Inhibition = 26 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL383865	Inhibition = 36 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL384149	IC50 = 1.6 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL384317	Inhibition = 38 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL384422	Inhibition = 80 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL384808	Not Active	Inhibition of Mycobacterium tuberculosis InhA at 20 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL385214	IC50 = 0.89 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL385262	Inhibition = 51 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL385294	IC50 = 1.49 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL385297	IC50 > 100 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL385570	Not Active	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL385605	Not Active	Inhibition of Mycobacterium tuberculosis InhA at 20 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL385650	Inhibition = 70 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL385650	IC50 = 1.29 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL385850	Not Active	Inhibition of Mycobacterium tuberculosis InhA at 20 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL386127	Not Active	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL386229	Inhibition = 30 %	Inhibition of Mycobacterium tuberculosis InhA at 1.5 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL386229	Inhibition = 90 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL386252	IC50 = 14.5 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL386324	IC50 = 0.85 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL386329	Inhibition > 90 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL386329	Inhibition = 72 %	Inhibition of Mycobacterium tuberculosis InhA at 1.5 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL386329	IC50 = 0.32 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL386417	Not Active	Inhibition of Mycobacterium tuberculosis InhA at 20 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL386587	Inhibition = 0 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL386655	Inhibition = 90 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL386655	IC50 = 1.39 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL386691	Not Active	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL386825	Not Active	Inhibition of Mycobacterium tuberculosis InhA at 20 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL386878	Inhibition = 5 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL386896	Inhibition = 3 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL387074	Inhibition = 20 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL387186	IC50 = 3.14 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL387284	IC50 = 5.55 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL387284	Inhibition > 50 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL387423	Inhibition = 80 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL387464	Not Active	Inhibition of Mycobacterium tuberculosis InhA at 20 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL392127	IC50 = 0.4 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL392127	Inhibition = 99 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL393216	Inhibition = 74 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL393403	Inhibition = 67 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL394432	IC50 > 100 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL394433	IC50 = 13.87 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL398031	IC50 = 6.26 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL398032	IC50 = 15.47 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL398895	Inhibition = 12 %	Inhibition of Mycobacterium tuberculosis InhA at 100 uM	http://www.ncbi.nlm.nih.gov/pubmed/17560106
CHEMBL400711	Inhibition = 25 %	Inhibition of Mycobacterium tuberculosis InhA at 700 uM	http://www.ncbi.nlm.nih.gov/pubmed/17560106
CHEMBL404983	Ki = 1 nM	Inhibition of Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL404983	IC50 = 5600 nM	Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL404984	Ki = 1 nM	Inhibition of Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL404984	IC50 = 1090 nM	Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL405653	IC50 = 1200 nM	Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL405653	Ki = 1 nM	Inhibition of Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL405655	IC50 = 236 nM	Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL405655	Ki = 1 nM	Inhibition of Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL407242	Not Active	Inhibition of Mycobacterium tuberculosis InhA at 20 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL407324	IC50 = 2360 nM	Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL407324	Ki = 1 nM	Inhibition of Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL408149	IC50 = 1315 nM	Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL408149	Ki = 1 nM	Inhibition of Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL410709	Inhibition = 50 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL411394	IC50 = 3.51 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL414086	Inhibition > 90 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL414086	Inhibition = 65 %	Inhibition of Mycobacterium tuberculosis InhA at 1.5 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL414086	IC50 = 0.62 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL415226	IC50 > 100 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL424724	Inhibition = 96 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL424724	IC50 = 0.41 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL424903	Inhibition = 89 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL424903	IC50 = 3.39 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL425259	IC50 = 0.97 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL426150	IC50 > 100 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL426702	IC50 = 0.85 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL426702	Inhibition > 90 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL426702	Inhibition = 70 %	Inhibition of Mycobacterium tuberculosis InhA at 1.5 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL428967	IC50 = 3220 nM	Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL428967	Ki = 1 nM	Inhibition of Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL429275	IC50 > 100 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL429332	Ki = 1 nM	Inhibition of Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL429332	IC50 > 100000 uM	Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL429994	IC50 = 6.05 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL430180	IC50 = 3.07 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL437002	IC50 = 14.11 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17723305
CHEMBL439530	IC50 = 28.02 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL441373	IC50 = 0.39 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL441373	IC50 = 2100 nM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL441373	Inhibition = 97 %	Inhibition of Mycobacterium tuberculosis InhA at 15 uM	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL441373	IC50 = 255 nM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL444361	IC50 = 23.12 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL454588	IC50 = 75 uM	inhibition of Mycobacterium tuberculosis InhA after 20 mins by fluorometric assay	http://www.ncbi.nlm.nih.gov/pubmed/12141869
CHEMBL454589	Not Active	inhibition of Mycobacterium tuberculosis InhA at 100 uM after 20 mins by fluorometric assay	http://www.ncbi.nlm.nih.gov/pubmed/12141869
CHEMBL458877	Inhibition = 91 %	Inhibition of Mycobacterium tuberculosis InhA at 40 uM	http://www.ncbi.nlm.nih.gov/pubmed/15917508
CHEMBL505886	Ki = 1 nM	Inhibition of Mycobacterium tuberculosis Enoyl-[acyl-carrier-protein] reductase	http://www.ncbi.nlm.nih.gov/pubmed/18393405
CHEMBL505886	IC50 = 5 nM	Inhibition of Mycobacterium tuberculosis recombinant InhA expressed in Escherichia coli using trans-2-dodecenoyl-coenzyme-A as substrate	http://www.ncbi.nlm.nih.gov/pubmed/22483635
CHEMBL539344	IC50 = 62 nM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/17034137
CHEMBL539395	IC50 = 5.13 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/19428156
CHEMBL539723	IC50 = 10.96 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/19428156
CHEMBL540475	IC50 = 5.01 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/19428156
CHEMBL540477	IC50 = 3.47 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/19428156
CHEMBL549456	IC50 = 9.55 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/19428156
CHEMBL550333	IC50 = 5.01 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/19428156
CHEMBL550334	IC50 = 4.07 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/19428156
CHEMBL550610	IC50 = 6.17 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/19428156
CHEMBL551621	IC50 = 2.14 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/19428156
CHEMBL551683	IC50 = 8.71 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/19428156
CHEMBL552222	IC50 = 4.37 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/19428156
CHEMBL553790	IC50 = 4.68 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/19428156
CHEMBL554270	IC50 = 3.63 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/19428156
CHEMBL557836	IC50 = 10.72 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/19428156
CHEMBL558073	IC50 = 13.8 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/19428156
CHEMBL558336	IC50 = 19.95 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/19428156
CHEMBL558464	IC50 = 3.31 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/19428156
CHEMBL558660	IC50 = 1.35 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/19428156
CHEMBL559811	IC50 = 17.78 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/19428156
CHEMBL560086	IC50 = 10.47 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/19428156
CHEMBL560605	IC50 = 19.95 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/19428156
CHEMBL560606	IC50 = 52.48 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/19428156
CHEMBL560683	IC50 = 10.47 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/19428156
CHEMBL560684	IC50 = 7.08 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/19428156
CHEMBL561485	IC50 = 11.48 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/19428156
CHEMBL564612	IC50 = 6.17 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/19428156
CHEMBL565062	IC50 = 1.82 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/19428156
CHEMBL565129	IC50 = 10 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/19428156
CHEMBL570080	IC50 = 12.02 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/19428156
CHEMBL571677	IC50 = 7.24 uM	Inhibition of Mycobacterium tuberculosis InhA	http://www.ncbi.nlm.nih.gov/pubmed/19428156
CHEMBL849	Inhibition = 37 %	Inhibition of Mycobacterium tuberculosis InhA using 2-trans-decenoyl-CoA as substrate at 10 uM after 5 mins using by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21975068
CHEMBL849	IC50 = 3 uM	inhibition of Mycobacterium tuberculosis InhA after 20 mins by fluorometric assay	http://www.ncbi.nlm.nih.gov/pubmed/12141869
CHEMBL849	Ki = 0.2 uM	Inhibition of Mycobacterium tuberculosis H37RV InhA	http://www.ncbi.nlm.nih.gov/pubmed/18457948
CHEMBL849	Inhibition > 99 %	Inhibition of Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21 using trans-2-dodecenoyl-Coenzyme A as substrate at 10 uM by spectrophotometry	http://www.ncbi.nlm.nih.gov/pubmed/21944473
CDD-1766	None	None	None
CDD-254	None	None	None
CDD-342489	None	None	None
CDD-343056	None	None	None
CDD-343076	None	None	None
CDD-353	None	None	None

Off-target activity - ligand based from TIBLE

View results in TIBLE page

Predicted off-target	Method	Summary	Full results
Cellular retinoic acid-binding protein 2 1CBS	PharmMapper	7 hydroph + 2 HB + 1 pos/neg + 0 arom	Link
Aldose reductase 2DUX	PharmMapper	4 hydroph + 5 HB + 1 pos/neg + 2 arom	Link
Transthyretin 1RLB	PharmMapper	9 hydroph + 1 HB + 0 pos/neg + 0 arom	Link
Cellular retinoic acid-binding protein 2 3CBS	PharmMapper	6 hydroph + 2 HB + 1 pos/neg + 0 arom	Link
Mitogen-activated protein kinase 14 1ZZL	PharmMapper	4 hydroph + 3 HB + 0 pos/neg + 0 arom	Link
Enoyl-[acyl-carrier-protein] reductase (NADH)	PASS	Pa = 0.982 & SM = CHEMBL849	Link
Cystathionine beta-synthase	PASS	Pa = 0.857 & SM = CHEMBL849	Link
JAK2 expression	PASS	Pa = 0.816 & SM = CHEMBL849	Link
Insulysin	PASS	Pa = 0.746 & SM = CHEMBL239673	Link
Arachidonate 12-lipoxygenase	SEA	E_value = 6.62e-24 & MaxTC = 0.36	Link
anandamine membrabe transporter [-]	SEA	E_value = 1.01e-18 & MaxTC = 0.48	Link
Sphingosine 1-phosphate receptor Edg-6	SEA	E_value = 5.18e-16 & MaxTC = 0.39	Link
Phosphodiesterase 4A	SEA	E_value = 6.79e-16 & MaxTC = 0.61	Link

Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.

Data not available

STITCH interactions

Chemical Name	Confidence score	Molecular Weight
triclosanPubChem	0.998	289.542
NAD+PubChem	0.997	663.425
5ppPubChem	0.987	256.34
geqPubChem	0.979	393.48
Th3PubChem	0.979	357.594
DB07222PubChem	0.979	334.84
DB07155PubChem	0.979	286.369
4piPubChem	0.979	293.403
8PCPubChem	0.979	346.207
DB07090PubChem	0.979	334.84
DB07188PubChem	0.979	355.259
DB07192PubChem	0.979	365.265
6PPPubChem	0.941	270.366
8PPPubChem	0.941	298.419
deuteriumPubChem	0.9	2.01588
TCuPubChem	0.9	284.393
dihydronicotinamide formycin dinucleotidePubChem	0.9	665.441
JPMPubChem	0.9	345.219
protiumPubChem	0.9	2.01576
hydroxyl radicalsPubChem	0.9	17.0073
1dGPubChem	0.9	850.515
ZidPubChem	0.9	768.519
dimethyl sulphoxidePubChem	0.9	78.1334
2-methyl-2,4-pentanediolPubChem	0.9	118.174
H(+)PubChem	0.9	2.01588
L-lysinePubChem	0.9	146.188
14PPPubChem	0.9	382.579
INH-NAD adductPubChem	0.9	770.535
(4s)-2-Methyl-2,4-PentanediolPubChem	0.9	118.174
reduced nicotinamide adenine dinucleotidePubChem	0.9	665.441
DG1PubChem	0.9	851.523
carbon dioxidePubChem	0.9	44.0095
JPJPubChem	0.9	359.246
isoniazidPubChem	0.883	137.139
ethionamidePubChem	0.875	166.243
DB03363PubChem	0.8	663.425

Rv1484

UniProt ID : P9WGR1 - INHA_MYCTU

View results in TIBLE page

View results in TIBLE page