Rv3841

Tuberculist information
Gene namebfrB
Protein functionBacterioferritin BfrB
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)4314.18
Molecular mass(da)20442
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 181
	  		  	1    MTEYEGPKTKFHALMQEQIHNEFTAAQQYVAIAVYFDSEDLPQLAKHFYSQAVEERNHAM   60
			  	61   MLVQHLLDRDLRVEIPGVDTVRNQFDRPREALALALDQERTVTDQVGRLTAVARDEGDFL  120
			  	121  GEQFMQWFLQEQIEEVALMATLVRVADRAGANLFELENFVAREVDVAPAASGAPHAAGGR  180
			  	181  L

Known structures in the PDB
PDB ID3OJ5
Total residue count4536
Number of chains24
MethodX-RAY
Resolution2.85
PDB ID3QD8
Total residue count4344
Number of chains24
MethodX-RAY
Resolution3
PDB ID3UNO
Total residue count4536
Number of chains24
MethodX-RAY
Resolution2.5
1 19 37 55 73 91 109 127 145 163 181 Range: 12 to 149  |  Coverage: 75% Ferritin Range: 6 to 164  |  Coverage: 87% 1 Range: 1 to 174  |  Coverage: 95% 1
Number of amino acids : 181
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
FerritinPF0021012-149
Mtb Structural Proteome models
Model Number1
Model nameRv3841
Template1S3Q    APDBCREDO
Template coverage3_164
Template Identity(%)28.3
Model coverage(%)87.3
Normalized DOPE score-1.476

Structure Models from Chopin
Model Number1
Profile1.20.1260.10
Click for model details
zscore14.95
Residue begin1
Residue end174
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3841Gene nameConfidence Score
Rv2428ahpC0.92
Rv3846sodA0.92
Rv3846sodA0.92
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
Fe(III)PubChem0.95355.845
zincPubChem0.85565.409
sulfatePubChem0.81996.0626
hydron sulfatePubChem0.778196.157
glycerolPubChem0.77692.0938
desferrioxaminePubChem0.703560.684