Rv3837c

Tuberculist information
Gene nameRv3837c
Protein functionProbable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase)
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)4311.01
Molecular mass(da)25019.1
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 232
	  		  	1    MSGRLVLLRHGQSYGNVERRLDTLPPGTALTPLGRDQARAFARSGCRRPALLAHSVAIRA   60
			  	61   YQTAAVVAAELDMVAHEVAGIHEVQVGELENRNDDEAVAEFNATYSRWHRGELDVPLPGG  120
			  	121  ETANDVLDRYLPVLADLRMRYLDDGDWDGDIVVVSHSAAIRLAAAVLAGVDGNFVLDNHL  180
			  	181  ENVESVVLAPITDGRWSCVQWGLRKPPFCPDPAEAAASPVTHAVTSSTDPMG

Known structures in the PDB
No Known structures
1 24 47 70 93 116 139 162 185 208 231 Range: 4 to 163  |  Coverage: 68% His_Phos_1 Range: 3 to 220  |  Coverage: 93% 1 Range: 1 to 228  |  Coverage: 97% 1
Number of amino acids : 232
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
His_Phos_1PF003004-163
Mtb Structural Proteome models
Model Number1
Model nameRv3837c
Template1QHF    APDBCREDO
Template coverage1_240
Template Identity(%)22.9
Model coverage(%)93.5
Normalized DOPE score0.193

Structure Models from Chopin
Model Number1
Profilec.60.1.1 - 3.40.50.1240
Click for model details
zscore31.72
Residue begin1
Residue end228
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3837cGene nameConfidence Score
Rv1437pgk0.903
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions