Rv3795
Tuberculist information
| Gene name | embB |
| Protein function | Integral membrane indolylacetylinositol arabinosyltransferase EmbB (arabinosylindolylacetylinositol synthase) |
| Functional category(tuberculist) | cell wall and cell processes |
| Gene location(kb) | 4246.51 |
| Molecular mass(da) | 118021 |
| External sites | TB Database TubercuList WebTB |
|---|
Protein sequence
Number of amino acids : 1098
1 MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQ 60 61 RGQLGSVTAPLISLTPVDFTATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSA 120 121 QRVDVTDRNVVILSVPREQVTSPQCQRIEVTSTHAGTFANFVGLKDPSGAPLRSGFPDPN 180 181 LRPQIVGVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIALWRLD 240 241 QLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFGFLLWHVIGANSSDD 300 301 GYILGMARVADHAGYMSNYFRWFGSPEDPFGWYYNLLALMTHVSDASLWMRLPDLAAGLV 360 361 CWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNNGLRPEGIIALGSLVTYVLIE 420 421 RSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVS 480 481 PMLAAGTVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRR 540 541 FGFLITALCLFTAVFIMLRRKRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFA 600 601 AVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLLALCWATTNGWWYVSSYGVPFNSAM 660 661 PKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIRALTTAPVPIVAGFMAAVFVA 720 721 SMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGDSGSWGPLGPL 780 781 GGVNPVGFTPNGVPEHTVAEAIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPA 840 841 RVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAAGKIAGNSVLHGYTPGQTVVL 900 901 EYAMPGPGALVPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDW 960 961 IAVTPPRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSA 1020 1021 KKLDTDTWEDGTNGGLLGITDLLLRAHVMATYLSRDWARDWGSLRKFDTLVDAPPAQLEL 1080 1081 GTATRSGLWSPGKIRIGP
Known structures in the PDB
No Known structures
Number of amino acids : 1098
Domains assigned based on sequence.
Mtb Structural proteome models
CHOPIN models
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models| Structural/Functional domain family | Pfam acc.no./SCOP ID | Domain Region | |
|---|---|---|---|
| Arabinose_trans | PF04602 | 18-690 | |
| Arabino_trans_C | PF14896 | 718-1097 |
| Model Number | 1 |
| Profile | 2.60.120.610 Click for model details |
|---|---|
| zscore | 26.43 |
| Residue begin | 52 |
| Residue end | 213 |
| Model Number | 2 |
| Profile | f.24.1.1 - 1.20.210.10 Click for model details |
|---|---|
| zscore | 4.33 |
| Residue begin | |
| Residue end |
View results in TIBLE page
| Name | Affinity | Assay description | DOI |
|---|---|---|---|
| CDD-1761 | None | None | None |
View results in TIBLE page
| Predicted off-target | Method | Summary | Full results |
|---|---|---|---|
| Tyrosine-protein phosphatase non-receptor type 1 1Q6J | PharmMapper | 5 hydroph + 1 HB + 2 pos/neg + 0 arom | Link |
| Tyrosine-protein phosphatase non-receptor type 1 1KAK | PharmMapper | 3 hydroph + 1 HB + 2 pos/neg + 0 arom | Link |
| Tyrosine-protein phosphatase non-receptor type 1 1KAV | PharmMapper | 4 hydroph + 3 HB + 1 pos/neg + 0 arom | Link |
| Aldo-keto reductase family 1 member C2 1IHI | PharmMapper | 3 hydroph + 3 HB + 1 pos/neg + 0 arom | Link |
| Retinoic acid receptor RXR-beta 1H9U | PharmMapper | 8 hydroph + 1 HB + 1 pos/neg + 0 arom | Link |
| Superoxide dismutase | PASS | Pa = 0.807 & SM = CDD-1761 | Link |
| Thrombocytopoiesis | PASS | Pa = 0.762 & SM = CDD-1761 | Link |
Data not available
