Rv3627c

Tuberculist information
Gene nameRv3627c
Protein functionConserved protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)4065.9
Molecular mass(da)46834.3
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 461
	  		  	1    MGPTRWRKSTHVVVGAAVLAFVAVVVAAAALVTTGGHRAGVRAPAPPPRPPTVKAGVVPV   60
			  	61   ADTAATPSAAGVTAALAVVAADPDLGKLAGRITDALTGQELWQRLDDVPLVPASTNKILT  120
			  	121  AAAALLTLDRQARISTRVVAGGQNPQGPVVLVGAGDPTLSAAPPGQDTWYHGAARIGDLV  180
			  	181  EQIRRSGVTPTAVQVDASAFSGPTMAPGWDPADIDNGDIAPIEAAMIDAGRIQPTTVNSR  240
			  	241  RSRTPALDAGRELAKALGLDPAAVTIASAPAGARQLAVVQSAPLIQRLSQMMNASDNVMA  300
			  	301  ECIGREVAVAINRPQSFSGAVDAVTSRLNTAHIDTAGAALVDSSGLSLDNRLTARTLDAT  360
			  	361  MQAAAGPDQPALRPLLDLLPIAGGSGTLGERFLDAATDQGPAGWLRAKTGSLTAINSLVG  420
			  	421  VLTDRSGRVLTFAFISNEAGPNGRNAMDALATKLWFCGCTT

Known structures in the PDB
No Known structures
1 47 93 139 185 231 277 323 369 415 461 Range: 72 to 241  |  Coverage: 36% Peptidase_S13 Range: 236 to 454  |  Coverage: 47% Peptidase_S13 Range: 78 to 457  |  Coverage: 82% 1 Range: 1 to 170  |  Coverage: 36% 1 Range: 72 to 241  |  Coverage: 36% 2 Range: 236 to 405  |  Coverage: 36% 3
Number of amino acids : 461
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Peptidase_S13PF0211372-241
Peptidase_S13PF02113236-454
Mtb Structural Proteome models
Model Number1
Model nameRv3627c
Template1W79    APDBCREDO
Template coverage11_459
Template Identity(%)30.3
Model coverage(%)82.2
Normalized DOPE score-0.156

Structure Models from Chopin
Model Number1
Profilee.3.1.3
Click for model details
zscore8.81
Residue begin1
Residue end170
Model Number2
Profilee.3.1.3
Click for model details
zscore8.81
Residue begin72
Residue end241
Model Number3
Profilee.3.1.3
Click for model details
zscore8.81
Residue begin236
Residue end405
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3627cGene nameConfidence Score
Rv2153cmurG0.926
Rv2153cmurG0.926
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
lipid intermediate IIPubChem0.91920.24
C05898PubChem0.91920.24