Rv3625c

Tuberculist information
Gene namemesJ
Protein functionPossible cell cycle protein MesJ
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)4063.9
Molecular mass(da)34129.9
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 323
	  		  	1    MDRQSAVAQLRAAAEQFARVHLDACDRWSVGLSGGPDSLALTAVAARLWPTTALIVDHGL   60
			  	61   QPGSATVAETARIQAISLGCVDARVLCVQVGAAGGREAAARSARYSALEEHRDGPVLLAH  120
			  	121  TLDDQAETVLLGLGRGSGARSIAGMRPYDPPWCRPLLGVRRSVTHAACRELGLTAWQDPH  180
			  	181  NTDRRFTRTRLRTEVLPLLEDVLGGGVAEALARTATALREDTDLIDTIAAQALPGAAVAG  240
			  	241  SRGQELSTSALTALPDAVRRRVIRGWLLAGGATGLTDRQIRGVDRLVTAWRGQGGVAVGS  300
			  	301  TLRGQRLVAGRRDGVLVLRREPV

Known structures in the PDB
No Known structures
1 33 65 97 129 161 193 225 257 289 321 Range: 27 to 194  |  Coverage: 51% ATP_bind_3 Range: 246 to 296  |  Coverage: 15% TilS Range: 1 to 316  |  Coverage: 97% 1 Range: 1 to 228  |  Coverage: 70% 1 Range: 205 to 309  |  Coverage: 32% 2
Number of amino acids : 323
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
ATP_bind_3PF0117127-194
TilSPF09179246-296
Mtb Structural Proteome models
Model Number1
Model nameRv3625c
Template1WY5    APDBCREDO
Template coverage1_311
Template Identity(%)24.4
Model coverage(%)97.5
Normalized DOPE score0.379

Structure Models from Chopin
Model Number1
Profilec.26.2.5
Click for model details
zscore38.11
Residue begin1
Residue end228
Model Number2
Profiled.229.1.1
Click for model details
zscore8.23
Residue begin205
Residue end309
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3625cGene nameConfidence Score
Rv3624chpt0.994
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions