Rv3583c

Tuberculist information
Gene nameRv3583c
Protein functionPossible transcription factor
Functional category(tuberculist)regulatory proteins
Gene location(kb)4025.06
Molecular mass(da)17907.4
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 162
	  		  	1    MIFKVGDTVVYPHHGAALVEAIETRTIKGEQKEYLVLKVAQGDLTVRVPAENAEYVGVRD   60
			  	61   VVGQEGLDKVFQVLRAPHTEEPTNWSRRYKANLEKLASGDVNKVAEVVRDLWRRDQERGL  120
			  	121  SAGEKRMLAKARQILVGELALAESTDDAKAETILDEVLAAAS

Known structures in the PDB
PDB ID4ILU
Total residue count170
Number of chains1
MethodX-RAY
Resolution2.3
PDB ID4KBM
Total residue count571
Number of chains2
MethodX-RAY
Resolution2.11
PDB ID4KMC
Total residue count80
Number of chains1
MethodX-RAY
Resolution2.15
PDB ID4MFR
Total residue count170
Number of chains1
MethodX-RAY
Resolution2.5
1 17 33 49 65 81 97 113 129 145 161 Range: 2 to 112  |  Coverage: 67% CarD_CdnL_TRCF Range: 5 to 161  |  Coverage: 96% 1 Range: 1 to 72  |  Coverage: 43% 1
Number of amino acids : 162
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
CarD_CdnL_TRCFPF025592-112
Mtb Structural Proteome models
Model Number1
Model nameRv3583c
Template2EYQ    APDBCREDO
Template coverage479_619
Template Identity(%)23.4
Model coverage(%)95.7
Normalized DOPE score1.077

Structure Models from Chopin
Model Number1
Profileb.34.18.1
Click for model details
zscore9.37
Residue begin1
Residue end72
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3583cGene nameConfidence Score
Rv3581cispF0.952
Rv3582cispD0.95
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions